Studies in the field of validation of alternative methods to the use of laboratory animals in biomedical research
The Joint Research Centre (JRC) has published a call for proposals for the completion of studies on the following subjects: - Alternative methods for replacing, reducing and/or removing the use of laboratory animals in the production of vaccines, quality control and the development of safety criteria; - The definition and evaluation of the pre-validation procedure within the context of the validation of alternative methods, especially the drawing up of procedures involving transferability and evaluation of the performance of protocols of tests prior to the official validation of appropriate test methods. The interaction between the different laboratories with experience in the development and evaluation of standardized procedures is to be provided; - The development of an integrated approach for predicting systemic toxicity using biocynetic models on computer and biological in-vitro test methods for the "various end-points" as alternative methods to the use of laboratory animals in biomedical research. Tender documentation may be obtained from: European Commission Joint Research Centre Institute for the Environment Mr. Marafante ECVAM (European Centre for the Validation of Alternative Methods) TP 580 I-21020 Ispra (VA) Tel. +39-332-789144; Fax +39-332-785336