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Intelligent intra-oral medicine delivery micro-system to treat addiction and chronic diseases

Objective

IntelliDrug is aimed at developing an intelligent micro- and nano- system to provide an alternative approach for the treatment of addiction and chronic diseases. Chronic diseases and Drug addiction are among the most severe human problems, the latter being a major motive of crime and social instability. The continuous and endless efforts required from treating personnel and the afflicted persons further compromise the quality of life and give rise to severe compliance problems with therapy. In addition, limited effectiveness and adverse side effects are the result of the currently used medication administration methods. The proposed project IntelliDrug is aimed at obviating these problems.

The proposed innovation will be reached by developing an intra-oral micro-system, which contains a medication replacement reservoir and releases the medication in a controlled, intelligent manner according to the patient needs, in periods lasting days, weeks or months. The device will be reloaded in a simple non-invasive way. The micro-system comprises a medication release mechanism, a built-in intelligence, micro-sensors and micro-actuators, and a remote control. This project explores the application potential of micro-nano technology and investigates the integration technologies required to establish the nano to macro interface and to have "nano" interact with the ambient. IntelliDrug deals with research and development of key technologies, such as biosensors and secure communication, low volume controlled drug handling, and the component integration into wearable systems, to manage health status.

The resulting micro-system will help afflicted persons to put an end to their personal misery, to run a life as close as possible to normal and even to turn into a productive member of our society. It also will contribute to strengthen European research, cooperation and industry.

Funding Scheme

STREP - Specific Targeted Research Project

Coordinator

ASSUTA MEDICAL CENTERS LTD
Address
62 Jabotinsky St.
62748 Tel Aviv
Israel

Participants (14)

ASM - CENTRUM BADAN I ANALIZ RYNKU SP. Z.O.O.
Poland
Address
Grunwaldzka 5
99-301 Kunto
CHARITE-UNIVERSITATSMEDIZIN BERLIN
Germany
Address
Schumannstrasse 20
10117 Berlin
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
Address
Hansastrasse 27C
80686 Muenchen
HAHN-SCHICKARD-GESELLSCHAFT FUER ANGEWANDTE FORSCHUNG E.V.
Germany
Address
Wilhelm-schickard-strasse 10
78052 Villingen-schwenningen
HOSPITAL CLINICO SAN CARLOS DE MADRID INSALUD
Spain
Address
Lugar Ciudad Universi
28040 Madrid
ISRAEL ANTI DRUG AUTHORITY
Israel
Address
7 Kanfei Nesharim St.
91039 Jerusalem
LYCORED BIO LTD
Israel
Address
Technology Park, Pharan 10
81103 Yavneh
MEDICAL TECHNOLOGY PROMEDT CONSULTING GMBH
Germany
Address
Kleiner Moorweg 4
25436 Tornesch
POLITECHNIKA WARSZAWSKA
Poland
Address
Plac Politechniki 1
00-661 Warszawa
RELSOFT SYSTEM LTD.
Israel
Address
17/A Lazarov St.
75654 Reshon Le-zion
TELEFONICA INVESTIGACION Y DESARROLLO SA UNIPERSONAL
Spain
Address
Calle Emilio Vargas 6
28043 Madrid
UNIVERSITA DEGLI STUDI DI NAPOLI FEDERICO II
Italy
Address
Corso Umberto 1
80138 Napoli
UNIVERSITA DEGLI STUDI DI PALERMO
Italy
Address
Piazza Marina, 61
90133 Palermo
VALTRONIC SA
Switzerland
Address
92, Vallee De Joux
1343 Les Charbonnieres