Objective SABIO is a multidisciplinary project involving the emerging fields of micro-nano technology, photonics, fluidics and bio-chemistry, targeting to contribute to the development of intelligent diagnosis for the healthcare of the future. SABIO will address this objective through the demonstration of a compact polymer-based and silicon-based CMOS-compatible micro-nano system. It integrates optical biosensors for label-free biomolecular recognition based on a novel photonic structure named slot-waveguide with immobilised biomolecular receptors on its surface.This structure offers the possibility of confinement and guidance of light in a nanometer-size void channel enhancing the interaction between an optical probe and biomolecular complexes (antibody-antigen). A slot-waveguide interferometric biosensor is predicted to exhibit a surface concentration detection-limit lower than 1 pg/mm2. that is the state-of-the-art in label-free integrated optical biosensors, with additional advantages such as the possibility of multiplexed assay, which, together with reduced reaction volumes, leads to the ability to perform rapid multianalyte sensing tests, offering further advantageous possibility of quantitatively assaying several parameters simultaneously (e.g. several cancer-associated antigens in one sample or several diseases antigens). Consequently, statistical analysis of these results can potentially increase the reliability of a diagnostic over single-parameter assays. In addition, SABIO has the potential to be fast and easy to use, making routine screening of diseases more cost-effective.The ultimate targeted by SABIO is demonstrating the fast diagnostics 'outside' of laboratory settings (eg. at 'point of care', in such as General Practitioner's surgery, in the field or in urgent situations). A final demonstrator consisting of a packaged biochip will be used on clinical samples in order to detect important diseases such as hepatitis B, CMV and liver cancer. Fields of science natural sciencesbiological sciencesbiochemistryengineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsbiosensorsmedical and health sciencesclinical medicineoncologyliver cancermedical and health sciencesclinical medicinesurgerymedical and health scienceshealth sciencesinfectious diseases Programme(s) FP6-IST - Information Society Technologies: thematic priority under the specific programme "Integrating and strengthening the European research area" (2002-2006). Topic(s) IST-2004-2.4.2 - Technologies and devices for micro/nano-scale integration Call for proposal Data not available Funding Scheme STREP - Specific Targeted Research Project Coordinator UNIVERSIDAD POLITECNICA DE VALENCIA EU contribution No data Address See on map Total cost No data Participants (8) Sort alphabetically Sort by EU Contribution Expand all Collapse all BAYER (SCHWEIZ) AG Switzerland EU contribution No data Address GRUBENSTRASSE 6 8045 ZUERICH See on map Total cost No data FARFIELD SCIENTIFIC LIMITED United Kingdom EU contribution No data Address FARFIELD HOUSE, SOUTHMERE COURT, ELECTRA WAY CW1 6GU CREWE See on map Total cost No data KHERION TECHNOLOGY LIMITED United Kingdom EU contribution No data Address 19A LYNDEWODE ROAD CB1 2HL CAMBRIDGE See on map Total cost No data KUNGLIGA TEKNISKA HOGSKOLAN Sweden EU contribution No data Address VALHALLAVAGEN 79 100 44 STOCKHOLM See on map Total cost No data MEDIZINISCHE UNIVERSITAET INNSBRUCK Austria EU contribution No data Address CHRISTOPH-PROBST PLATZ 1 6020 INNSBRUCK See on map Total cost No data MULTITEL ASBL Belgium EU contribution No data Address RUE PIERRE ET MARIE CURIE 2 7000 MONS See on map Total cost No data UNIVERSIDAD POLITECNICA DE MADRID Spain EU contribution No data Address AVENIDA RAMIRO DE MAEZTU 7 MADRID See on map Links Website Opens in new window Total cost No data UNIVERSITE PARIS-SUD France EU contribution No data Address 15, RUE GEORGES CLEMENCEAU 91405 ORSAY CEDEX See on map Total cost No data
