Objective
SABIO is a multidisciplinary project involving the emerging fields of micro-nano technology, photonics, fluidics and bio-chemistry, targeting to contribute to the development of intelligent diagnosis for the healthcare of the future. SABIO will address this objective through the demonstration of a compact polymer-based and silicon-based CMOS-compatible micro-nano system. It integrates optical biosensors for label-free biomolecular recognition based on a novel photonic structure named slot-waveguide with immobilised biomolecular receptors on its surface.
This structure offers the possibility of confinement and guidance of light in a nanometer-size void channel enhancing the interaction between an optical probe and biomolecular complexes (antibody-antigen). A slot-waveguide interferometric biosensor is predicted to exhibit a surface concentration detection-limit lower than 1 pg/mm2. that is the state-of-the-art in label-free integrated optical biosensors, with additional advantages such as the possibility of multiplexed assay, which, together with reduced reaction volumes, leads to the ability to perform rapid multianalyte sensing tests, offering further advantageous possibility of quantitatively assaying several parameters simultaneously (e.g. several cancer-associated antigens in one sample or several diseases antigens). Consequently, statistical analysis of these results can potentially increase the reliability of a diagnostic over single-parameter assays. In addition, SABIO has the potential to be fast and easy to use, making routine screening of diseases more cost-effective.
The ultimate targeted by SABIO is demonstrating the fast diagnostics 'outside' of laboratory settings (eg. at 'point of care', in such as General Practitioner's surgery, in the field or in urgent situations). A final demonstrator consisting of a packaged biochip will be used on clinical samples in order to detect important diseases such as hepatitis B, CMV and liver cancer.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry
- engineering and technology electrical engineering, electronic engineering, information engineering electronic engineering sensors biosensors
- medical and health sciences clinical medicine oncology liver cancer
- medical and health sciences clinical medicine surgery
- medical and health sciences health sciences infectious diseases
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.