Objective The ImmunoGrid is an implementation of virtual human immune system using grid technologies. It can simulate immune processes at natural scale and provides tools for applications in clinical immunology and the design of vaccines and immunotherapies. The developed set of tools will be validated with experimental data and used in clinical applications for development of immunotherapies in cancer and chronic infections. Computational models are applicable because immune system is complex and has combinatorial nature, experimental approaches are expensive, and there are restrictions on the experimentation that can be performed in humans.The ImmunoGrid project is highly relevant to the IST Call 4, its objectives, focus, and roadmaps. The target user groups are clinicians and the developers of the vaccines and immunotherapies. The ImmunoGrid applications will provide tools for clinicians and vaccine/immunotherapy developers for identification of optimal immunisation protocols. The unique component of this proposal is that it aims at connecting molecular level interactions (which regulate immune responses) with system level models (which study behaviour of the immune system as a whole). This is a novel approach to disease prevention and treatment which will help improve human health. Applications of the ImmunoGrid include modelling of the natural-size complex system on a large scale. Another important contribution of the ImmunoGrid will be the implementation of individual immune system models across the grid nodes.This fits well into the roadmaps for research and developments in ICT for health focusing on the development of an in silico model of a human being (virtual human).ImmunoGrid will be developed by an European consortium with members from Italy, France, UK, Denmark, and France and also from Singapore. The members of the consortium are the leading experts in computational immunology whose developments have been experimentally validated. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugsvaccinesmedical and health sciencesbasic medicineimmunologyimmunotherapynatural sciencescomputer and information sciencessoftwaresoftware applicationssimulation software Programme(s) FP6-IST - Information Society Technologies: thematic priority under the specific programme "Integrating and strengthening the European research area" (2002-2006). Topic(s) IST-2004-2.4.11 - Integrated biomedical information for better health Call for proposal Data not available Funding Scheme STREP - Specific Targeted Research Project Coordinator CONSORZIO INTERUNIVERSITARIO PER LA GESTIONE DEL CENTRO DI CALCOLO ELETTRONICO DELL'ITALIA NORD-ORIENTALE Address Via magnanelli 6/3 40033 Casalecchio di reno (bologna) Italy See on map EU contribution No data Participants (7) Sort alphabetically Sort by EU Contribution Expand all Collapse all ALMA MATER STUDIORUM-UNIVERSITA DI BOLOGNA Italy EU contribution € 0,00 Address Via zamboni 33 Bologna See on map Links Website Opens in new window Other funding No data BIRKBECK COLLEGE - UNIVERSITY OF LONDON United Kingdom EU contribution € 0,00 Address Malet street London See on map Links Website Opens in new window Other funding No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE France EU contribution € 0,00 Address 3, rue michel-ange Paris cedex 16 See on map Other funding No data CONSIGLIO NAZIONALE DELLE RICERCHE Italy EU contribution € 0,00 Address See on map Links Website Opens in new window Other funding No data DANMARKS TEKNISKE UNIVERSITET Denmark EU contribution € 0,00 Address Anker engelundsvej 1, bygning 101a 2800 Kgs. lyngby See on map Other funding No data THE UNIVERSITY OF QUEENSLAND Australia EU contribution € 0,00 Address QLD4072 Brisbane, queensland See on map Other funding No data UNIVERSITA DI CATANIA Italy EU contribution € 0,00 Address Piazza universita 2 95124 Catania See on map Other funding No data
