Objective
The ImmunoGrid is an implementation of virtual human immune system using grid technologies. It can simulate immune processes at natural scale and provides tools for applications in clinical immunology and the design of vaccines and immunotherapies. The developed set of tools will be validated with experimental data and used in clinical applications for development of immunotherapies in cancer and chronic infections. Computational models are applicable because immune system is complex and has combinatorial nature, experimental approaches are expensive, and there are restrictions on the experimentation that can be performed in humans.
The ImmunoGrid project is highly relevant to the IST Call 4, its objectives, focus, and roadmaps. The target user groups are clinicians and the developers of the vaccines and immunotherapies. The ImmunoGrid applications will provide tools for clinicians and vaccine/immunotherapy developers for identification of optimal immunisation protocols. The unique component of this proposal is that it aims at connecting molecular level interactions (which regulate immune responses) with system level models (which study behaviour of the immune system as a whole). This is a novel approach to disease prevention and treatment which will help improve human health. Applications of the ImmunoGrid include modelling of the natural-size complex system on a large scale. Another important contribution of the ImmunoGrid will be the implementation of individual immune system models across the grid nodes.
This fits well into the roadmaps for research and developments in ICT for health focusing on the development of an in silico model of a human being (virtual human).ImmunoGrid will be developed by an European consortium with members from Italy, France, UK, Denmark, and France and also from Singapore. The members of the consortium are the leading experts in computational immunology whose developments have been experimentally validated.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- medical and health sciences basic medicine immunology immunotherapy
- natural sciences computer and information sciences software software applications simulation software
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
40033 CASALECCHIO DI RENO (BOLOGNA)
Italy
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.