From Simplicity to Complexity: Crafting Molecular Architectures via Cascade Polyene Cyclizations

Project Information

CRAFTMOL

Grant agreement ID: 101000060

DOI

10.3030/101000060

EC signature date 18 December 2020

Start date 1 February 2022

End date 31 January 2027

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 998 767,00

EU contribution

€ 1 998 767,00

Coordinated by

UNIVERSITAET INNSBRUCK
Austria

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Development of a Synthetic Platform for <i>Ent</i>‐Pimaranes Reveals their Potential as Novel Non‐Redox Active Ferroptosis Inhibitors

Author(s): Immanuel Plangger, Alex Mühlsteiger, Julia Berger, Julian Feilner, Klaus Wurst, Andreas Koeberle, Solveigh C. Koeberle, Thomas Magauer
Published in: Chemistry – A European Journal, 2024, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202403811

Synthesis of Waixenicin A: Exploring Strategies for Nine-Membered Ring Formation​

Author(s): Christian Steinborn, Tatjana Huber, Julian Lichtenegger, Immanuel Plangger, Denis Höfler, Simon D. Schnell, Lara Weisheit, Peter Mayer, Klaus Wurst, Thomas Magauer
Published in: Chemistry - A European Journal, 2023, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202303489

A General Entry to <i>Ganoderma</i> Meroterpenoids: Synthesis of Applanatumol E, H, and I, Lingzhilactone B, Meroapplanin B, and Lingzhiol

Author(s): Alexander Rode, Nicolas Müller, Ondřej Kováč, Klaus Wurst, Thomas Magauer
Published in: Organic Letters, 2024, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.4c03192

A Divergent Polyene Cyclization for the Total Synthesis of Greenwayodendrines, Greenwaylactams, Polysin and Polyveoline

Author(s): Immanuel Plangger, Tobias Pinkert, Klaus Wurst, Thomas Magauer
Published in: Angewandte Chemie, 2023, ISSN 1521-3773
Publisher: Wiley-VCH
DOI: 10.1002/anie.202307719

Total Syntheses of (+)-Waixenicin A, (+)-9-Deacetoxy-14,15-deepoxyxeniculin, and (−)-Xeniafaraunol A

Author(s): Christian Steinborn, Tatjana Huber, Julian Lichtenegger, Immanuel Plangger, Klaus Wurst, and Thomas Magauer
Published in: Journal of the American Chemical Society, 2023, ISSN 1520-5126
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c03366

Correction to Synthesis of the Tetracyclic Spiro-naphthoquinone Chartspiroton

Author(s): Liesa Röder, Ivica Zamarija, Klaus Wurst, Thomas Magauer
Published in: Organic Letters, Issue 26, 2024, Page(s) 5056-5056, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.4c01557

Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations

Author(s): Feilner, Julian M.; Haut, Franz‐Lucas; Magauer, Thomas
Published in: Chemistry (Weinheim an Der Bergstrasse, Germany), Issue 1, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202005157

Short, Divergent, and Enantioselective Total Synthesis of Bioactive ent-Pimaranes

Author(s): Immanuel Plangger, Klaus Wurst, Thomas Magauer
Published in: Organic Letters, Issue 15237060, 2022, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.2c02843

Non-enzymatic methylcyclization of alkenes

Author(s): Immanuel Plangger, Elias Schmidhammer, Sebastian Schaar, Klaus Wurst, Maren Podewitz, Thomas Magauer
Published in: Nature Chemistry, 2025, ISSN 1755-4330
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-025-01774-3

Total Synthesis of Ganoapplanin Enabled by a Radical Addition/Aldol Reaction Cascade

Author(s): Nicolas Müller, Ondřej Kováč, Alexander Rode, Daniel Atzl, Thomas Magauer
Published in: Journal of the American Chemical Society, Issue 146, 2024, Page(s) 22937-22942, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.4c08291

Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products

Author(s): Julian M. Feilner; Immanuel Plangger; Klaus Wurst; Thomas Magauer
Published in: Chemistry (Weinheim an Der Bergstrasse, Germany), Issue 1, 2021, ISSN 0947-6539
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202101926

Non-peer reviewed articles (1)

Synthesis of the Tetracyclic Spiro-naphthoquinone Chartspiroton

Author(s): Liesa Röder, Klaus Wurst, Thomas Magauer
Published in: Organic Letters, Issue 26, 2024, Page(s) 3065-3068, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.4c00695