RAPID DISCOVERY AND DEVELOPMENT OF ENZYMES FOR NOVEL AND GREENER CONSUMER PRODUCTS

Project Information

RADICALZ

Grant agreement ID: 101000560

DOI 10.3030/101000560

Project closed

EC signature date 21 April 2021

Start date 1 June 2021

End date 31 May 2025

Funded under

• SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy

Total cost € 6 004 308,91

EU contribution € 6 004 308,75

Coordinated by

UNIVERSIDAD AUTONOMA DE MADRID
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

Initial communication pack
Advanced communication analysis

Websites, patent fillings, videos etc. (1)

Visual ID, web & social media

Visual ID web social media

Open Research Data Pilot (1)

Data management plan-1st version

Data management plan the initial version will be delivered at month 6 with updates at month 24 and 48

Publications

Peer reviewed articles (15)

Materials and methods for droplet microfluidic device fabrication

Author(s): Katherine S. Elvira, Fabrice Gielen, Scott S. H. Tsai, Adrian M. Nightingale
Published in: Lab on a Chip, Issue 22, 2024, Page(s) 859-875, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d1lc00836f

On the need for gate-to-gate environmental metrics in biocatalysis: fatty acid hydration catalyzed by oleate hydratases as a case study

Author(s): Pablo Dominguez de María
Published in: Green Chemistry, Issue 24, 2022, Page(s) 9620-9628, ISSN 1463-9270
Publisher: Royal Society of Chemistry
DOI: 10.5281/zenodo.7584741

Biocatalysis in Water or in Non-Conventional Media? Adding the CO2 Production for the Debate

Author(s): Domínguez de María, P., Kara, S., Gallou, F.
Published in: Molecules, Issue 28(18), 2023, Page(s) 6452, ISSN 1420-3049
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules28186452

Enzymatic Synthesis of Hydroxycinnamic Acid Amides in Water Using the Promiscuous Hydrolase/Acyltransferase PestE from Pyrobaculum calidifontis VA1

Author(s): Uwe T. Bornscheuer, Benjamin Baumert, Henrik Terholsen, Clemens Cziegler, Isabel Thier, Christoffel P. S. Badenhorst, Karsten Siems
Published in: Synlett, Issue 35, 2024, Page(s) 1062-1066, ISSN 0936-5214
Publisher: Georg Thieme Verlag
DOI: 10.1055/a-2268-8035

High-Throughput Steady-State Enzyme Kinetics Measured in a Parallel Droplet Generation and Absorbance Detection Platform

Author(s): Stefanie Neun, Liisa van Vliet, Florian Hollfelder, Fabrice Gielen
Published in: Analytical Chemistry, Issue 94, 2023, Page(s) 16701-16710, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.2c03164

Discovery and Biotechnological Exploitation of Glycoside-Phosphorylases

Author(s): Ao Li, Mounir Benkoulouche, Simon Ladeveze, Julien Durand, Gianluca Cioci, Elisabeth Laville, Gabrielle Potocki-Veronese
Published in: International Journal of Molecular Sciences, Issue 23(6), 2022, Page(s) 3043, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23063043

Primary and secondary waste in (bio)catalysis: What matters is not what is produced but what permanently remains!

Author(s): Pablo Domínguez de María
Published in: Current Opinion in Green and Sustainable Chemistry, Issue 52, 2025, Page(s) 101003, ISSN 2452-2236
Publisher: x
DOI: 10.1016/j.cogsc.2025.101003

Bacterial α-Glucan and Branching Sucrases from GH70 Family: Discovery, Structure–Function Relationship Studies and Engineering

Author(s): Manon Molina, Gianluca Cioci, Claire Moulis, Etienne Séverac and Magali Remaud-Siméon
Published in: Microorganisms, Issue 9(8), 2021, Page(s) 1607, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms9081607

Selective Enzymatic C−H‐Oxyfunctionalization for the Efficient Synthesis of Grevillic Acid

Author(s): Clemens Cziegler, Benjamin Baumert, Christoffel P. S. Badenhorst, Karsten Siems, Uwe T. Bornscheuer
Published in: Advanced Synthesis & Catalysis, Issue 367, 2025, ISSN 1615-4150
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/adsc.202401421

General equations to estimate the CO₂ production of (bio)catalytic reactions in early development stages

Author(s): Pablo Domínguez de María
Published in: RSC Sustainability, Issue 2, 2025, Page(s) 3817-3825, ISSN 2753-8125
Publisher: x
DOI: 10.1039/d4su00535j

Promiscuous acyltransferases for ester and amide synthesis in aqueous solution

Author(s): Benjamin Baumert, Hannes Meinert, Clemens Cziegler, Henrik Terholsen, Thomas Bayer, Uwe T. Bornscheuer
Published in: Catalysis Today, Issue 442, 2025, Page(s) 114925, ISSN 0920-5861
Publisher: Elsevier BV
DOI: 10.1016/j.cattod.2024.114925

Green solvents and biocatalysis: A bigger picture

Author(s): Domínguez de María. Pablo
Published in: EFB Bioeconomy Journal, Issue 3, 2023, Page(s) 100056, ISSN 2667-0410
Publisher: European Federation of Biotechnology
DOI: 10.1016/j.bioeco.2023.100056

On the fate of deep eutectic solvents after their use as reaction media: the CO2 production during downstream and ultimate disposal

Author(s): Domínguez de María, Pablo; Kara, Selin
Published in: RSC Sustainability, Issue 2(3), 2024, Page(s) 608-615, ISSN 2753-8125
Publisher: Royal Society of Chemistry
DOI: 10.1039/d4su00021h

Optimization of Biocatalytic Rhododendrol Production from Biogenic Rhododendrol Glycosides

Author(s): Emerik Leaković, Karsten Siems, Michel Feussi Tala, Antonia Habazin, Zvjezdana Findrik Blažević, Ana Vrsalović Presečki
Published in: ACS Sustainable Chemistry & Engineering, Issue 12, 2025, Page(s) 16329-16339, ISSN 2168-0485
Publisher: American Chemical Society
DOI: 10.1021/acssuschemeng.4c05889

Thermostable in vitro transcription-translation compatible with microfluidic droplets

Author(s): Ana L J L Ribeiro, Patricia Pérez-Arnaiz , Mercedes Sánchez-Costa , Lara Pérez 1 3 , Marcos Almendros, Liisa van Vliet , Fabrice Gielen, Jesmine Lim, Simon Charnock, Florian Hollfelder , J Eduardo González-Pastor, José Berenguer, Aurelio Hidalgo
Published in: Microbial and Cell Factories, Issue 23, 2024, Page(s) 169, ISSN 1475-2859
Publisher: BioMed Central
DOI: 10.1186/s12934-024-02440-y