Reconnecting transmission to global tuberculosis control by mapping pathogen transmission events to host infection status

Publications

Genomic approaches for tuberculosis management and control

Auteurs: Comas, Iñaki; López, Mariana G.; Chiner-Oms, Álvaro; Farhat, Maha R.; Semuto Ngabonziza, Jean Claude; Campos, Josefina; Moreno-Molina, Miguel
Publié dans: The Challenge of Tuberculosis in the 21st Century (ERS Monograph), Numéro 1, 2023, Page(s) 178–190, ISBN 978-1-84984-170-2
Éditeur: European Respiratory Society
DOI: 10.1183/2312508x.10025022

The structural role of SARS-CoV-2 genetic background in the emergence and success of spike mutations: The case of the spike A222V mutation

Auteurs: Ginex, T., Marco-Marín, C., Wieczór, M., Mata, C.P., Krieger, J., Ruiz-Rodriguez, P., López-Redondo, M.L., Francés-Gómez, C., Melero, R., Sánchez-Sorzano, C.Ó., Martínez, M., Gougeard, N., Forcada-Nadal, A., Zamora-Caballero, S., Gozalbo-Rovira, R., Sanz-Frasquet, C., Arranz, R., Bravo, J., Rubio, V., Marina, A., Geller, R., Comas, I., Gil, C., Coscolla, M., Orozco, M., Llácer, J.L., Cara
Publié dans: Plos Pathogens, 2022, ISSN 1553-7366
Éditeur: Public Library of Science
DOI: 10.1371/journal.ppat.1010631

Accuracy of an amplicon-sequencing nanopore approach to identify variants in tuberculosis drug-resistance-associated genes

Auteurs: Carla Mariner-Llicer; Galo A. Goig; Laura Zaragoza-Infante; Manuela Torres-Puente; Luis Villamayor; David Navarro; Rafael Borras; Álvaro Chiner-Oms; Iñaki Comas
Publié dans: Microbial Genomics, 2021, ISSN 2057-5858
Éditeur: Microbiology Society
DOI: 10.1099/mgen.0.000740

Phenogenomics of Mycobacterium abscessus

Auteurs: Comas, I., Moreno-Molina, M.
Publié dans: Nature Microbiology, 2021, ISSN 2058-5276
Éditeur: Springer
DOI: 10.1038/s41564-022-01217-6

The 2021 WHO catalogue of Mycobacterium tuberculosis complex mutations associated with drug resistance: a genotypic analysis

Auteurs: Walker, T.M., Fowler, P.W., Knaggs, J., Hunt, M., Peto, T.E., Walker, A.S., Crook, D.W., Walker, T.M., Miotto, P., Cirillo, D.M., Köser, C.U., Knaggs, J., Iqbal, Z., Hunt, M., Chindelevitch, L., Farhat, M.R., Comas, I., Posey, J., Omar, S.V., Peto, T.E., Walker, A.S., Crook, D.W., Suresh, A., Uplekar, S., Laurent, S., Colman, R.E., Rodwell, T.C., Nathanson, C.-M., Zignol, M., Ismail, N., Rodwell,
Publié dans: The Lancet Microbe, 2021, ISSN 2666-5247
Éditeur: Elsevier
DOI: 10.1016/s2666-5247(21)00301-3

The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant

Auteurs: López, M.G., Chiner-Oms, Á., García de Viedma, D., Ruiz-Rodriguez, P., Bracho, M.A., Cancino-Muñoz, I., D’Auria, G., de Marco, G., García-González, N., Goig, G.A., Gómez-Navarro, I., Jiménez-Serrano, S., Martinez-Priego, L., Ruiz-Hueso, P., Ruiz-Roldán, L., Torres-Puente, M., Alberola, J., Albert, E., Aranzamendi Zaldumbide, M., Bea-Escudero, M.P., Boga, J.A., Bordoy, A.E., Canut-Blasco
Publié dans: Nature Genetics, 2021, ISSN 1061-4036
Éditeur: Nature Publishing Group
DOI: 10.1038/s41588-021-00936-6

Gene evolutionary trajectories in Mycobacterium tuberculosis reveal temporal signs of selection

Auteurs: Chiner-Oms, A., Lopez, M.G., Moreno-Molina, M., Furio, V., Comas, I.
Publié dans: Proceedings of the National Academy of Sciences of the United States of America, 2022, ISSN 0027-8424
Éditeur: National Academy of Sciences
DOI: 10.1073/pnas.2113600119

An evolutionary functional genomics approach identifies novel candidate regions involved in isoniazid resistance in Mycobacterium tuberculosis

Auteurs: Furió, V., Moreno-Molina, M., Chiner-Oms, Á., Villamayor, L.M., Torres-Puente, M., Comas, I.
Publié dans: Communications Biology, 2021, ISSN 2399-3642
Éditeur: Springer
DOI: 10.1038/s42003-021-02846-z

Tracking SARS-CoV-2 introductions in Mozambique using pandemic-scale phylogenies: a retrospective observational study

Auteurs: Martínez-Martínez FJ, Massinga AJ, De Jesus Á, Ernesto RM, Cano-Jiménez P, Chiner-Oms Á, Gómez-Navarro I, Guillot-Fernández M, Guinovart C, Sitoe A, Vubil D, Bila R, Gujamo R, Enosse S, Jiménez-Serrano S, Torres-Puente M, Comas I, Mandomando I, López MG, Mayor A.
Publié dans: The Lancet Global Health, Numéro Jun;11(6), 2023, Page(s) e933-e941, ISSN 2214-109X
Éditeur: Elsevier BV
DOI: 10.1016/s2214-109x(23)00169-9

Population-based sequencing of Mycobacterium tuberculosis reveals how current population dynamics are shaped by past epidemics

Auteurs: Cancino-Muñoz, I., López, M.G., Torres-Puente, M., Villamayor, L.M., Borrás, R., Borrás-Máñez, M., Bosque, M., Camarena, J.J., Colijn, C., Colomer-Roig, E., Colomina, J., Escribano, I., Esparcia-Rodríguez, O., García-García, F., Gil-Brusola, A., Gimeno, C., Gimeno-Gascón, A., Gomila-Sard, B., Gónzales-Granda, D., Gonzalo-Jiménez, N., Guna-Serrano, M.R., López-Hontangas, J.L., Martín-
Publié dans: eLife, 2022, ISSN 2050-084X
Éditeur: eLife Sciences Publications
DOI: 10.7554/elife.76605

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