Project description
Breaking new ground in the field of adult hippocampal neurogenesis
The hippocampus is a brain area critical for learning and memory. Impairment of adult hippocampal neurogenesis is linked to cognitive dysfunction and mood dysregulation in rodents. The hippocampus is particularly vulnerable to damage at the early stages of Alzheimer’s disease. In this context, the ERC-funded HumAN project will shed light on the mechanisms that control the maturation and synaptic integration of newly generated cells in human beings. It will also identify the pathophysiology of neurodegenerative and psychiatric diseases, thereby facilitating the identification of potential novel therapeutic targets for these as yet incurable conditions. The project will determine, for the first time, whether new neurons integrate efficiently into the human hippocampus.
Fields of science
Programme(s)
Funding Scheme
ERC-COG - Consolidator GrantHost institution
Beneficiaries (2)
Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.
28049 Madrid