EcoWizard: innovative nanomaterials require ecologically based safety assessment

Project Information

ECOWIZARD

Grant agreement ID: 101002123

DOI

10.3030/101002123

EC signature date 13 April 2021

Start date 1 May 2021

End date 30 April 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

UNIVERSITEIT LEIDEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (32)

A framework for guiding safe and sustainable‐by‐design innovation

Author(s): Carlos Felipe Blanco, Paul Behrens, Martina Vijver, Willie Peijnenburg, Joris Quik, Stefano Cucurachi
Published in: Journal of Industrial Ecology, 2024, ISSN 1088-1980
Publisher: MIT Press
DOI: 10.1111/jiec.13609

What is there to gain and lose from plant-derived nano-enabled pesticides: Eugenol-loaded nanocarriers exert long-lived effects on non-target freshwater invertebrate communities

Author(s): Tom A.P. Nederstigt, Victor N. Huijer, Dennis Planjer, Felice J.M. Eekhout, S. Henrik Barmentlo, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Journal of Hazardous Materials, Issue 496, 2025, Page(s) 139560, ISSN 0304-3894
Publisher: Elsevier BV
DOI: 10.1016/j.jhazmat.2025.139560

Zooplankton community turnover in response to a novel TiO2-coated nano-formulation of carbendazim and its constituents

Author(s): Tom A.P. Nederstigt, Bo Bode, J. Ruud van Ommen, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Environmental Pollution, Issue Volume 333, 15 September 2023, 121894, 2023, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2023.121894

Nanoplastics causes extensive congenital malformations during embryonic development by passively targeting neural crest cells

Author(s): Meiru Wang, Martin Rücklin, Robert E. Poelmann, Carmen L. de Mooij, Marjolein Fokkema, Gerda E.M. Lamers, Merijn A.G. de Bakker, Ernest Chin, Lilla J. Bakos, Federica Marone, Bert J. Wisse, Marco C. de Ruiter, Shixiong Cheng, Luthfi Nurhidayat, Martina G. Vijver, Michael K. Richardson
Published in: Environment International, Issue Volume 173, March 2023, 107865, 2023, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.107865

Nano- and microplastics commonly cause adverse impacts on plants at environmentally relevant levels: A systematic review

Author(s): Laura J. Zantis, Caterina Borchi, Martina G. Vijver, Willie Peijnenburg, Sara Di Lonardo, Thijs Bosker
Published in: Science of The Total Environment, Issue Volume 867, 1 April 2023, 161211, 2023, ISSN 0048-9697
Publisher: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.161211

Exploring the potential of in silico machine learning tools for the prediction of acute Daphnia magna nanotoxicity

Author(s): SurendraBalraadjsing, Willie J.G.M.Peijnenburg, Martina G.Vijver
Published in: Chemosphere, Issue Volume 307, Part 2, November 2022, 2022, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2022.135930

Using machine learning to predict adverse effects of metallic nanomaterials to various aquatic organisms

Author(s): Yunchi Zhou; Ying Wang; Willie Peijnenburg; Martina G. Vijver; Surendra Balraadjsing; Wenhong Fan
Published in: Environmental Science and Technology, Issue 1, 2023, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.2c07039

Trophic transfer of Cu nanoparticles in a simulated aquatic food chain

Author(s): Qi Yu, Zhenyan Zhang, Fazel Abdolahpur Monikh, Juan Wu, Zhuang Wang, Martina G. Vijver, Thijs Bosker, Willie J.G.M. Peijnenburg
Published in: Ecotoxicology and Environmental Safety, Issue Volume 242, 1 September 2022, 2022, ISSN 0147-6513
Publisher: Academic Press
DOI: 10.1016/j.ecoenv.2022.113920

Eugenol-Loaded Nanocarriers Exert Particle-Specific Adverse Effects on <i>Daphnia magna</i> Populations

Author(s): Bregje W. Brinkmann, Lan Dupuis, Sam Houdijk, Pelle Wattel, Cástor Salgado, Andrea Brunelli, José F. Fernández, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Environmental Science &amp; Technology, Issue 59, 2025, Page(s) 16293-16303, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.5c03624

Modeling the Toxicokinetics of Suspensions of Soluble Metallic Nanomaterials

Author(s): Guangchao Chen, Vivi Rottschäfer, Martina G. Vijver, Willie J. G. M. Peijnenburg
Published in: Chemical Research in Toxicology, 2024, ISSN 0893-228X
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrestox.4c00177

Towards Sustainable Chemical Process Design: Revisiting the Integration of Life Cycle Assessment

Author(s): Bartolomeus Häussling Löwgren, Christian Hoffmann, Martina G. Vijver, Bernhard Steubing, Giuseppe Cardellini
Published in: Journal of Cleaner Production, 2025, Page(s) 144831, ISSN 0959-6526
Publisher: Elsevier BV
DOI: 10.1016/j.jclepro.2025.144831

Chronic toxicity of core–shell SiC/TiO2 (nano)-particles to Daphnia magna under environmentally relevant food rations in the presence of humic acid

Author(s): Serwatowska K.J., Nederstigt T.A.P., Peijnenburg W.J.G.M. & Vijver M.G
Published in: Nanotoxicology, 2024, ISSN 1743-5390
Publisher: Informa Healthcare
DOI: 10.1080/17435390.2024.2321873

Impacts of a nano-enabled pesticide formulation (nTiO2-coated carbendazim) and its constituents on the freshwater snail Lymnaea stagnalis &amp; damselfly Ischnura elegans assessed via in-situ bioassays

Author(s): Tom A.P. Nederstigt, Richard K.M. Frische, Jesse Ouwehand, Martina G. Vijver
Published in: Ecotoxicology and Environmental Safety, Issue 303, 2025, Page(s) 118809, ISSN 0147-6513
Publisher: Academic Press
DOI: 10.1016/j.ecoenv.2025.118809

Addressing the Data Scarcity Problem in Ecotoxicology via Small Data Machine Learning Methods

Author(s): Ying Wang, Jinchu Dong, Yunchi Zhou, Yinghao Cheng, Xiaoli Zhao, Willie J. G. M. Peijnenburg, Martina G. Vijver, Kenneth M. Y. Leung, Wenhong Fan, Fengchang Wu
Published in: Environmental Science &amp; Technology, Issue 59, 2025, Page(s) 5867-5871, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.5c00510

Sustainability Claims of Nanoenabled Pesticides Require a More Thorough Evaluation

Author(s): Nederstigt T.A.P, Brinkmann B.W., Peijnenburg W.J.G.M, Vijver M.G
Published in: Environmental Science & Technology Article ASAP, 2024, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.3c10207

Microbial function matters: Microbiome-aware nano-ecotoxicology needs functional endpoints besides compositional data

Author(s): Jesse Ouwehand, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Chemosphere, Issue 369, 2024, Page(s) 143905, ISSN 0045-6535
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2024.143905

Building species trait-specific nano-QSARs: Model stacking, navigating model uncertainties and limitations, and the effect of dataset size

Author(s): Balraadjsing S., Peijnenburg W.J.G.M. & Vijver M.G.
Published in: Environment International, 2024, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2024.108764

Knowns and unknowns of novel entities

Author(s): Melymuk, L.; Carter, L.; Ng, C.A.; Liu, Q.; Vijver, M.G.; Fantke, P.; Baun, A.
Published in: One Earth, Issue 5 (10), 2022, Page(s) 1067-1069, ISSN 2590-3330
Publisher: Cell Press
DOI: 10.1016/j.oneear.2022.09.010

Accumulation kinetics of polystyrene nano- and microplastics in the waterflea Daphnia magna and trophic transfer to the mysid Limnomysis benedeni

Author(s): Qi Yu, Tom A.P. Nederstigt, Zhuang Wang, Juan Wu, Thijs Bosker, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Environmental Pollution, Issue 363, 2024, Page(s) 125029, ISSN 0269-7491
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2024.125029

Machine learning-driven QSAR models for predicting the mixture toxicity of nanoparticles

Author(s): Fan Zhang, Zhuang Wang, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: Environment International, Issue 177 (2023) 108025, 2023, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.108025

Host and microbiome proteins in eco-coronas: abundance, physicochemical properties and binding partners

Author(s): Bregje W. Brinkmann, Zhiling Guo, Martina G. Vijver, Willie J. G. M. Peijnenburg, Andrew J. Chetwynd
Published in: Environmental Science: Nano, 2025, ISSN 2051-8153
Publisher: Royal Society of Chemistry
DOI: 10.1039/d5en00493d

Predicting the dissolution of metal-based nanoparticles by means of QSPRs and the effect of data augmentation

Author(s): Yuchao Song, Surendra Balraadjsing, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: NanoImpact, Issue 37, 2025, Page(s) 100547, ISSN 2452-0748
Publisher: Elsevier BV
DOI: 10.1016/j.impact.2025.100547

Application of Machine Learning in Nanotoxicology: A Critical Review and Perspective

Author(s): Yunchi Zhou, Ying Wang, Willie Peijnenburg, Martina G. Vijver, Surendra Balraadjsing, Zhaomin Dong, Xiaoli Zhao, Kenneth M. Y. Leung, Holly M. Mortensen, Zhenyu Wang, Iseult Lynch, Antreas Afantitis, Yunsong Mu, Fengchang Wu, Wenhong Fan
Published in: Environmental Science &amp; Technology, 2024, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.4c03328

The biodistribution of polystyrene nanoparticles administered intravenously in the chicken embryo

Author(s): Wang M., Chen S., Cheng S., Nederstigt T.A.P., Poelmann R.E., DeRuiter M.C., Lamers G.E.M., Willemse J.J., Mascitelli C., Vijver M.G. & Richardson M.K.
Published in: Environment International, 2024, ISSN 0160-4120
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2024.108723

Developing and verifying a quantitative dissolution model for metal-bearing nanoparticles in aqueous media

Author(s): Yuchao Song, Vivi Rottschäfer, Martina G. Vijver, Willie J. G. M. Peijnenburg
Published in: Environmental Science: Nano, Issue 10, 2024, Page(s) 1790-1799, ISSN 2051-8153
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3en00096f

Can Current Regulations Account for Intentionally Produced Nanoplastics?

Author(s): Fazel Abdolahpur Monikh, Steffen Foss Hansen, Martina G. Vijver, Esther Kentin, Maria Bille Nielsen, Anders Baun, Kristian Syberg, Iseult Lynch*, Eugenia Valsami-Jones, and Willie J.G.M. Peijnenburg
Published in: Environmental Science & Technology, Issue 2022, 56, 2022, Page(s) 3836-3839, ISSN 1520-5851
Publisher: ACS Publications
DOI: 10.1021/acs.est.2c00965

Toxicokinetics and Particle Number-Based Trophic Transfer of a Metallic Nanoparticle Mixture in a Terrestrial Food Chain

Author(s): Juan Wu, Jianqiang Sun*, Thijs Bosker, Martina G. Vijver, and Willie J. G. M. Peijnenburg
Published in: Environmental Science & Technology, Issue 2023, 57, 7, 2023, Page(s) 2792–2803, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.2c07660

Trimetal-based nanomaterials induced toxicity to plants: Does it differ from the toxicity of mixed and single-element nanoparticles?

Author(s): Yuchao Song, Mieke van Vlaardingen, Frank Senden, Willie J.G.M. Peijnenburg, Martina G. Vijver
Published in: HELIYON, Issue 2 December 2023, e23178, 2023, ISSN 2405-8440
Publisher: Elsevier Ltd
DOI: 10.1016/j.heliyon.2023.e23178

Generating Environmental Sampling and Testing Data for Micro- and Nanoplastics for Use in Life Cycle Impact Assessment

Author(s): Cecilia Askham; Valentina H. Pauna; Anne-Marie Boulay; Peter Fantke; Olivier Jolliet; Jérôme Lavoie; Andy M. Booth; Claire Coutris; Francesca Verones; Miriam Weber; Martina G. Vijver; Amy Lusher; Carla Hajjar
Published in: Science of the Total Environment, 859(2):160038, Issue Volume 859, Part 2, 10 February 2023, 160038, 2023, ISSN 1879-1026
Publisher: Elsevier ltd
DOI: 10.1016/j.scitotenv.2022.160038

Fate models of nanoparticles in the environment: a critical review and prospects

Author(s): Ruiyu Zhang, Xiaoxin Zheng, Wenhong Fan, Xiangrui Wang, Tianhui Zhao, Xiaoli Zhao, Willie J. G. M. Peijnenburg, Martina G. Vijver, Ying Wang
Published in: Environmental Science: Nano, Issue 12, 2025, Page(s) 3394-3412, ISSN 2051-8153
Publisher: Royal Society of Chemistry
DOI: 10.1039/d5en00342c

“Review and Prospects on the Ecotoxicity of Mixtures of Nanoparticles and Hybrid Nanomaterials”

Author(s): Fan Zhang, Zhuang Wang, Willie J. G. M. Peijnenburg, Martina G. Vijver
Published in: Environmental Science & Technology, 2022, ISSN 0013-936X
Publisher: American Chemical Society
DOI: 10.1021/acs.est.2c03333

Addressing grand ecological challenges in aquatic ecosystems: how can mesocosms be used to advance solutions?

Author(s): Samuel J. Macaulay, Erik Jeppesen, Ulf Riebesell, Jens C. Nejstgaard, Stella A. Berger, Aleksandra M. Lewandowska, Andreu Rico, Ben J. Kefford, Csaba F. Vad, David M. Costello, Haijun Wang, Iris Madge Pimentel, Joana Barcelos e Ramos, Jose González, Kristian Spilling, Lisette de Senerpont Domis, Maarten Boersma, Maria Stockenreiter, Mariana Meerhoff, Martina G. Vijver, Mary Kelly-Quinn, Meryem Be
Published in: Oikos, Issue 2025, 2025, ISSN 0030-1299
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/oik.11020

Other (1)

FLCafé11-E4: De dosis maakt niet langer het gif

Author(s): Martina Vijver (Universiteit Leiden)
Published in: 2025
Publisher: Studio Foodlog