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Regulatory rules and evolution of neuronal gene expression

Project description

Investigating the regulatory landscape of neuronal cell specialisation and evolution

Neuronal cells are characterised by a high degree of specialisation, which is necessary for complex brain functions. However, the regulatory mechanisms responsible for neuronal specification and evolution remain largely unknown. The EU-funded NEUROCODE project aims to study the landscape of transcription factors in different types of neuronal cells and how they cooperate to activate gene expression and drive neuron differentiation and specification. For this purpose, scientists will employ the nematode Caenorhabditis elegans as a model organism and single-cell technologies to unravel the regulatory mechanisms responsible for the evolution of neuronal cells. Results will provide fundamental information on brain development and function.

Call for proposal

ERC-2020-COG
See other projects for this call

Funding Scheme

ERC-COG - Consolidator Grant

Host institution

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 1 997 500

Beneficiaries (1)

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 1 997 500
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations