Emerging tools and methods to study cell signalling mediated by branched ubiquitin chains
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Author(s):
Matthew R. McFarland, Yogesh Kulathu
Published in:
Biochemical Society Transactions, Issue 53, 2025, Page(s) 579-592, ISSN 0300-5127
Publisher:
Portland Press, Ltd.
DOI:
10.1042/bst20253015
Elucidation of short linear motif-based interactions of the MIT and rhodanese domains of the ubiquitin-specific protease 8
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Author(s):
Aimiliani Konstantinou, Julia K. Varga, Alicia Córdova-Pérez, Leandro Simonetti, Lidia Gomez-Lucas, Ora Schueler-Furman, Norman E. Davey, Yogesh Kulathu, Ylva Ivarsson
Published in:
Biology Direct, Issue 20, 2025, ISSN 1745-6150
Publisher:
BioMed Central
DOI:
10.1186/s13062-025-00638-7
ATXN3 regulates lysosome regeneration after damage by targeting K48-K63-branched ubiquitin chains
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Author(s):
Maike Reinders, Bojana Kravic, Pinki Gahlot, Sandra Koska, Johannes van den Boom, Nina Schulze, Sophie Levantovsky, Stefan Kleine, Markus Kaiser, Yogesh Kulathu, Christian Behrends, Hemmo Meyer
Published in:
The EMBO Journal, Issue 44, 2026, ISSN 0261-4189
Publisher:
Nature Publishing Group
DOI:
10.1038/s44318-025-00517-x
VCP/p97-associated proteins are binders and debranching enzymes of K48–K63-branched ubiquitin chains
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Author(s):
Sven M. Lange, Matthew R. McFarland, Frederic Lamoliatte, Thomas Carroll, Logesvaran Krshnan, Anna Pérez-Ràfols, Dominika Kwasna, Linnan Shen, Iona Wallace, Isobel Cole, Lee A. Armstrong, Axel Knebel, Clare Johnson, Virginia De Cesare, Yogesh Kulathu
Published in:
Nature Structural & Molecular Biology, 2024, ISSN 1545-9993
Publisher:
Nature Publishing Group
DOI:
10.1038/s41594-024-01354-y