Engineering kidney organoids to study the interplay between Tissue Mechanics and Metabolism: from development to disease

Project Information

ENGINORG

Grant agreement ID: 101002478

DOI

10.3030/101002478

EC signature date 2 September 2021

Start date 1 October 2021

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 999 937,00

EU contribution

€ 1 999 937,00

Coordinated by

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (11)

Harnessing mechanobiology for kidney organoid research

Author(s): Zarina Nauryzgaliyeva, Iphigénie Goux Corredera, Elena Garreta and Nuria Montserrat
Published in: Frontiers in Cell and Developmental Biology, 2023, ISSN 2296-634X
Publisher: Frontiers
DOI: 10.3389/fcell.2023.1273923

Assessing kidney development and disease using kidney organoids and CRISPR engineering

Author(s): Safi W; Marco A; Moya D; Prado P; Garreta E; Montserrat N
Published in: Frontiers In Cell And Developmental Biology, Issue Frontiers In Cell And Developmental Biology. 10 948395, 2022, ISSN 2296-634X
Publisher: Frontiers Media Sa
DOI: 10.3389/fcell.2022.948395

Protocol for SARS-CoV-2 infection of kidney organoids derived from human pluripotent stem cells

Author(s): Garreta E, Moya-Rull D, Stanifer ML, Monteil V, Prado P, Marco A, Tarantino C, Gallo M, Jonsson G, Hagelkruys A, Mirazimi A, Boulant S, Penninger JM, Montserrat N.
Published in: Star Protoc, Issue Star Protoc. 3 (4): 101872, 2022, ISSN 2666-1667
Publisher: Cell Press, [2020]
DOI: 10.1016/j.xpro.2022.101872

Human induced pluripotent stem cell-derived kidney organoids toward clinical implementations

Author(s): Garreta, E; Nauryzgaliyeva, Z; Montserrat, N
Published in: Curr Opin Biomed Eng, Issue Curr Opin Biomed Eng. 20, 2022, ISSN 2468-4511
Publisher: Elsevier
DOI: 10.1016/j.cobme.2021.100346

Clinical grade ACE2 as a universal agent to block SARS-CoV-2 variants

Author(s): Monteil, V; Eaton, B; Postnikova, E; Murphy, M; Braunsfeld, B; Crozier, I; Kricek, F; Niederhofer, J; Schwarzbock, A; Breid, H; Devignot, S; Klingstrom, J; Thalin, C; Kellner, MJ; Christ, W; Havervall, S; Mereiter, S; Knapp, S; Jimenez, AS; Bugajska-Schretter, A; Dohnal, A; Ruf, C; Gugenberger, R; Hagelkruys, A; Montserrat, N; Kozieradzki, I; Ali, OH; Stadlmann, J; Holbrook, MR; Schmaljohn, C; Oos
Published in: Embo Molecular Medicine, Issue Embo Molecular Medicine. 14 (8): e15230, 2022, ISSN 1757-4676
Publisher: John Wiley & Sons Ltd.
DOI: 10.15252/emmm.202115230

P53-Independent G1-Cell Cycle Arrest Increases SARS-CoV-2 RNA Replication

Author(s): Clara Husser, Hyesoo Kwon, Klara Andersson, Sofia Appelberg, Nuria Montserrat , Ali Mirazimi and Vanessa M. Monteil
Published in: Microorganism, Issue 12 (3), 2024, ISSN 2076-2607
Publisher: MDPI
DOI: 10.3390/microorganisms12030443

Engineering physiological environments to advance kidney organoid models from human pluripotent stem cells

Author(s): Anisha Pahuja, Iphigénie Goux Corredera, Daniel Moya-Rull, Elena Garretaand Nuria Montserrat
Published in: Current Opinion in Cell Biology, 2024, ISSN 1879-0410
Publisher: Elsevier
DOI: 10.1016/j.ceb.2023.102306

Natural Hydrogels Support Kidney Organoid Generation and Promote in vitro Angiogenesis

Author(s): Elena Garreta, Daniel Moya-Rull, Andrés Marco, Gaia Amato, Asier Ullate-Agote, Carolina Tarantino, Maria Gallo, David Esporrín-Ubieto, Alberto Centeno, Amaia Vilas-Zornoza, Rafael Mestre, María Kalil, Izar Gorroñogoitia, Ane Miren Zaldua, Samuel Sanchez, Laura Izquierdo Reyes, M. Eugenia Fernández-Santos, Felipe Prosper, Nuria Montserrat
Published in: Advanced Materials, 2024, ISSN 1521-4095
Publisher: Wiley-VCH GmbH
DOI: 10.1002/adma.202400306

Dissecting nephron morphogenesis using kidney organoids from human pluripotent stem cells

Author(s): Garreta E; Nauryzgaliyeva Z; Marco A; Safi W; Montserrat N
Published in: Current Opinion In Genetics & Development, Issue Current Opinion In Genetics & Development. 72 22-29, 2022, ISSN 0959-437X
Publisher: Elsevier BV
DOI: 10.1016/j.gde.2021.10.002

A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells

Author(s): Garreta E; Prado P; Stanifer ML; Monteil V; Marco A; Ullate-Agote A; Moya-Rull D; Vilas-Zornoza A; Tarantino C; Romero JP; Jonsson G; Oria R; Leopoldi A; Hagelkruys A; Gallo M; González F; Domingo-Pedrol P; Gavaldà A; Del Pozo CH; Hasan Ali O; Ventura-Aguiar P; Campistol JM; Prosper F; Mirazimi A; Boulant S; Penninger JM; Montserrat N
Published in: Cell Metabolism, Issue Cell Metabolism. 34 (6): 857-873, 2022, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2022.04.009

Crimean–Congo haemorrhagic fever virus uses LDLR to bind and enter host cells

Author(s): Vanessa M. Monteil , Shane C. Wright  , Matheus Dyczynski, Max J. Kellner, Sofia Appelberg  , Sebastian W. Platzer , Ahmed Ibrahim,Hyesoo Kwon , Ioannis Pittarokoilis , Mattia Mirandola, Georg Michlits  Stephanie Devignot, Elizabeth Elder , Samir Abdurahman, Sándor Bereczky, Binnur Bagci, Sonia Youhanna, Teodor Aastrup, Volker M. Lauschke, Cristiano Salata , Nazif Elaldi ,
Published in: Nature Microbiology, 2024, ISSN 2058-5276
Publisher: Springer Nature
DOI: 10.1038/s41564-024-01672-3