Mechanoradicals in Collagen

Project Information

RADICOL

Grant agreement ID: 101002812

DOI

10.3030/101002812

EC signature date 27 January 2021

Start date 1 June 2021

End date 31 May 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 998 873,00

EU contribution

€ 1 998 873,00

Coordinated by

RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Intrinsically disordered region of talin’s FERM domain functions as an initial PIP2 recognition site

Author(s): Jannik Buhr; Florian Franz; Frauke Gräter
Published in: Biophysical Journal, Issue 1, 2023, ISSN 1542-0086
Publisher: Cell Press
DOI: 10.1016/j.bpj.2023.02.020

Allosteric activation of vinculin by talin

Author(s): Florian Franz; Rafael Tapia-Rojo; Sabina Winograd-Katz; Rajaa Boujemaa-Paterski; Wenhong Li; Tamar Unger; Shira Albeck; Camilo Aponte-Santamaria; Sergi Garcia-Manyes; Ohad Medalia; Benjamin Geiger; Frauke Gräter
Published in: Nature Communications, Issue 2, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39646-4

Bond dissociation energies of X–H bonds in proteins

Author(s): Treyde AW, Riedmiller K, Gräter F
Published in: RSC Advances, 2022, ISSN 2046-2069
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2ra04002f

DOPA residues endow collagen with radical scavenging capacity

Author(s): Kurth M, Barayeu U, Gharibi H, Kuzhelev A, Riedmiller K, Zilke J, Noack K, Denysenkov V, Kappl R, Prisner TF, Zubarev RA, Dick TP, Gräter F
Published in: Angew. Chem. Int. Ed., 2023, ISSN 2692-8205
Publisher: Wiley
DOI: 10.1101/2023.01.23.524231

Predicting reaction barriers of hydrogen atom transfer in proteins

Author(s): Kai Riedmiller; Patrick Reiser; Elizaveta Bobkova; Kiril Maltsev; Ganna Gryn'ova; Pascal Friederich; Frauke Gräter
Published in: Chemical Science, Issue 1, 2024, ISSN 2041-6539
Publisher: RSC
DOI: 10.26434/chemrxiv-2023-7hntk

Hydropersulfides inhibit lipid peroxidation and ferroptosis by scavenging radicals

Author(s): Uladzimir Barayeu; Danny Schilling; Mohammad Eid; Thamara Nishida Xavier da Silva; Lisa Schlicker; Nikolina Mitreska; Christopher Zapp; Frauke Gräter; Aubry K. Miller; Reinhard Kappl; Almut Schulze; José Pedro Friedmann Angeli; Tobias P. Dick
Published in: Nature Chemical Biology, Issue 19, 2022, Page(s) 28-37, ISSN 1552-4450
Publisher: Nature Publishing Group
DOI: 10.1038/s41589-022-01145-w

Collagen breaks at weak sacrificial bonds taming its mechanoradicals

Author(s): Rennekamp B, Karfusehr C, Kurth M, Ünal A, Riedmiller K, Gryn’ova G, Hudson DM, Gräter F
Published in: Nature Communications, 2023, ISSN 2692-8205
Publisher: Nature
DOI: 10.1101/2022.10.17.512491

ColBuilder: A server to build collagen fibril models

Author(s): Obarska-Kosinska A, Rennekamp B, Ünal A, Gräter F
Published in: Biophysical Journal, 2021, ISSN 0006-3495
Publisher: Biophysical Society
DOI: 10.1016/j.bpj.2021.07.009