Development of a chemical biology toolbox for deciphering the ubiquitin code

Project Information

Ubl-tool

Grant agreement ID: 101003289

DOI

10.3030/101003289

EC signature date 11 February 2021

Start date 1 September 2021

End date 28 February 2027

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 997 717,00

EU contribution

€ 1 997 717,00

Coordinated by

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion

Author(s): Maria Weyh; Marie-Lena Jokisch; Tuan-Anh Nguyen; Maximilian Fottner; Kathrin Lang
Published in: Nature Chemistry, 2024, ISSN 1755-4349
Publisher: Nature Publishing Group
DOI: 10.1038/s41557-024-01500-5

Site-Specific Protein Labeling and Generation of Defined Ubiquitin-Protein Conjugates Using an Asparaginyl Endopeptidase

Author(s): Maximilian Fottner; Johannes Heimgärtner; Maximilian Gantz; Rahel Mühlhofer; Timon Nast-Kolb; Kathrin Lang
Published in: Journal of the American Chemical Society, 144 (29), 2022, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c02191

Genetic Code Expansion Approaches to Decipher the Ubiquitin Code

Author(s): Vera Wanka, Maximilian Fottner, Marko Cigler, Kathrin Lang
Published in: Chemical Reviews, Issue 124, 2024, Page(s) 11544-11584, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.4c00375

A modular toolbox to generate complex polymeric ubiquitin architectures using orthogonal sortase enzymes

Author(s): Maximilian Fottner, Maria Weyh, Stefan Gaussmann, Dominic Schwarz, Michael Sattler & Kathrin Lang
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26812-9