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Phthalocyanine-biopolymeric nanoparticle delivery systems for cancer photodynamic therapy

Project description

Nanoparticles for the delivery of photodynamic therapy agents

Photodynamic therapy (PDT) is a minimally invasive treatment that combines photosensitising drugs, oxygen and light to kill cancer cells. It is a selective approach with minimal side effects on normal tissues, offering a promising alternative to standard chemotherapy. Despite its approval for clinical use 20 years ago, PDT still finds limited use in most cancer types. The EU-funded BIOnanoPDT project proposes to incorporate phthalocyanine as the photosensitising drug into functionalised biodegradable polymeric nanoparticles to target tumour cells. This will help to address issues associated with the selectivity, aggregation and low water solubility of photosensitising drugs, enhancing the application of PDT in the clinic.

Call for proposal

H2020-WF-2018-2020

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Sub call

H2020-WF-02-2019

Coordinator

CENTRUM MATERIALOW POLIMEROWYCH IWEGLOWYCH POLSKA AKADEMIA NAUK*CMPIW PAN
Net EU contribution
€ 149 625,60
Address
Ul. M Curie Sklodowskiej 34
41 819 Zabrze
Poland

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Region
Makroregion południowy Śląskie Gliwicki
Activity type
Research Organisations
Other funding
€ 0,00