Gastrointestinal Tract on Chip - An automated microfluidics-based modular device for complete simulation of the processes of digestion and absorption of orally ingested bioactive compounds

Project Information

GASTRIC

Grant agreement ID: 101003440

DOI 10.3030/101003440

Project closed

EC signature date 30 September 2020

Start date 16 October 2020

End date 15 October 2022

Funded under

• SPREADING EXCELLENCE AND WIDENING PARTICIPATION

Total cost € 159 815,04

EU contribution € 159 815,04

Coordinated by

INTERNATIONAL IBERIAN NANOTECHNOLOGY LABORATORY
Portugal

Publications

Peer reviewed articles (5)

From mouth to gut: microfluidic in vitro simulation of human gastro-intestinal digestion and intestinal permeability

Author(s): Miguel Xavier, Patrícia M. Rodrigues, Mafalda D. Neto, Maria I. Guedes, Victor Calero, Lorenzo Pastrana and Catarina Gonçalves
Published in: Analyst, 2023, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2an02088b

Recent Advances in Cell-Based In Vitro Models to Recreate Human Intestinal Inflammation

Author(s): Maria Helena Macedo, Mafalda Dias Neto, Lorenzo Pastrana, Catarina Gonçalves, Miguel Xavier
Published in: Advanced Science, Issue 2301391, 2023, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202301391

Effect of prebiotic fermentation products from primary human gut microbiota on an in vitro intestinal model

Author(s): Inês A.Parente, Migue lXavier, Dalila Roupar, Isabel Amado, Paulo Berni, Cláudia Botelho, José A.Teixeira, Lorenzo Pastrana, Clarisse Nobre, Catarina Gonçalves
Published in: Journal of Functional Foods, Issue 96, 2022, ISSN 1756-4646
Publisher: Elsevier BV
DOI: 10.1016/j.jff.2022.105200

Partitioning of Small Hydrophobic Molecules into Polydimethylsiloxane in Microfluidic Analytical Devices

Author(s): Patrícia M Rodrigues, Miguel Xavier, Victor Calero, Lorenzo Pastrana, Catarina Gonçalves
Published in: Micromachines, 2022, ISSN 2072-666X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi13050713

Safety and fate of nanomaterials in food: The role of in vitro tests

Author(s): Miguel Xavier, Inês A. Parente, Patrícia M. Rodrigues, Miguel A. Cerqueira, Lorenzo Pastrana, Catarina Gonçalves
Published in: Trends in Food Science & Technology, Issue 109, 2021, Page(s) 593-607, ISSN 0924-2244
Publisher: Elsevier BV
DOI: 10.1016/j.tifs.2021.01.050