Descripción del proyecto
Una nueva solución portátil para los escasos recursos de las UCI
Los sistemas sanitarios de todo el mundo se han visto abrumados por el aumento de pacientes gravemente enfermos con COVID-19 que requieren su ingreso en unidades de cuidados intensivos (UCI). Si bien las tasas exactas difieren entre los distintos Estados miembros de la Unión Europea, el 3-12 % de la población infectada necesita someterse a ventilación mecánica. La personalización del tratamiento hará posible un racionamiento más específico de los escasos recursos de las UCI. A partir de esta idea, el proyecto financiado con fondos europeos VASCOVID está desarrollando una plataforma de monitorización sanitaria portátil, no invasiva y en tiempo real que combina la espectroscopia del infrarrojo cercano con resolución temporal y la espectroscopia de correlación difusa. La solución permitirá realizar pruebas a gran escala de nuevas terapias y procedimientos dirigidos hacia la insuficiencia microvascular. Además, reducirá la incidencia de fracasos de la extubación (reintubación en un plazo de siete días) en las UCI.
Objetivo
As COVID-19 spreads worldwide, the surge in patients requiring intensive care unit (ICU) admission has been overwhelming to the healthcare systems. Critical care triage to allow the rationing of scarce ICU resources is needed but is hindered due to lack of personalization. The management of acute respiratory failure and hemodynamics is critical at the ICU. In fact, of the seven million COVID-19 cases (end of May 2020) 3-12% required mechanical ventilation which forms the primary target of VASCOVID where we focus on; (1) patient stratification derived from endothelial function evaluation, and, (2) evaluation of cardiopulmonary interactions that personalizes conservative ventilation strategies in order to avoid ventilator-induced lung injury and readiness to wean from the ventilator. VASCOVID will deploy and mature our portable, non-invasive and real-time health monitoring platform for this purpose. This platform combines two bio-photonics technologies, time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy, and is the fruit of long-term collaboration between core project partners in two European projects (BabyLux and LUCA) where high technology readiness level have been achieved for neuro-monitoring and thyroid cancer screening. VASCOVID will adapt the platform to meet the needs of a typical ICU dealing with COVID-19 and other patients requiring ventilation, as well as to leverage large-scale testing of new treatment procedures and therapies aimed to address microvascular impairment and to reduce extubation failure on ICU patients weaning out of mechanical ventilation life-support. The platform is easy to deploy, cost-effective and provides real-time fast results and its transition to clinical practice will be eased through this project by pushing CE certification. Our inter-disciplinary consortium is well-suited for these activities and will interact closely with our on-going clinical study spanning four countries and a dozen hospitals.
Ámbito científico
- agricultural sciencesagriculture, forestry, and fisheriesagriculturehorticulturefruit growing
- medical and health sciencesclinical medicinecritical care medicine
- medical and health scienceshealth sciencesinfectious diseasesRNA virusescoronaviruses
- medical and health sciencesclinical medicineoncology
- natural sciencesphysical sciencesopticsspectroscopy
Palabras clave
Programa(s)
Convocatoria de propuestas
H2020-SC1-PHE-CORONAVIRUS-2020-2
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SC1-PHE-CORONAVIRUS-2020-2-CNECT
Régimen de financiación
IA - Innovation actionCoordinador
08860 Castelldefels
España