BIO-PHOTONIC IMAGING OF THE INFANT BRAIN, THE MISSING LINK BETWEEN THE CELLULAR BRAIN DAMAGE AND THE NEUROVASCULAR UNIT DURING ACUTE ILLNESS

Project Information

TinyBrains

Grant agreement ID: 101017113

DOI

10.3030/101017113

Project closed

EC signature date 14 December 2020

Start date 1 January 2021

End date 30 June 2025

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Total cost

€ 3 773 357,50

EU contribution

€ 3 773 357,50

Coordinated by

FUNDACIO INSTITUT DE CIENCIES FOTONIQUES
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (4)

Communication kit
Communication and dissemination plan
Interim report on communication and dissemination activities
Communication kit update

Websites, patent fillings, videos etc. (1)

Project introduction animation or video

Publications

Peer reviewed articles (19)

Assessment of power spectral density of microvascular hemodynamics in skeletal muscles at very low and low-frequency via near-infrared diffuse optical spectroscopies

Author(s): Caterina Amendola, Mauro Buttafava, Talyta Carteano, Letizia Contini, Lorenzo Cortese, Turgut Durduran, Lorenzo Frabasile, Claudia Nunzia Guadagno, Umut Karadeinz, Michele Lacerenza, Jaume Mesquida, Shahrzad Parsa, Rebecca Re, Diego Sanoja Garcia, Sanathana Konugolu Venkata Sekar, Lorenzo Spinelli, Alessandro Torricelli, Alberto Tosi, Udo M. Weigel, Atif M Yaqub, Marta Zanoletti, Davi
Published in: Biomedical Optics Express, 2023, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.502618

Hybrid diffuse optical appraisal of peripheral and cerebral changes in critically ill patients receiving red blood cell transfusion

Author(s): Susanna Tagliabue, Anna Rey-Perez, Lourdes Exposito, Andrés F. Jimenez, Sara Valles Angulo, Federica Maruccia, Jonas B. Fischer, Michal Kacprzak, Maria A. Poca, Turgut Durduran
Published in: Biophotonics Discovery, Issue 2, 2025, ISSN 3005-4745
Publisher: Biophotonics Discovery
DOI: 10.1117/1.bios.2.1.015001

Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care

Author(s): M. Atif Yaqub, Marta Zanoletti, Lorenzo Cortese, Daniel Senciales Sánchez, Caterina Amendola, Lorenzo Frabasile, Umut Karadeniz, Jacqueline Martinez Garcia, Marta Martin, Jordi Cortes-Picas, Alba Caballer, Edgar Cortes, Sara Nogales, Alberto Tosi, Talyta Carteano, Diego Sanoja Garcia, Jakub Tomanik, Tessa Wagenaar, Hsiao Mui, Claudia Nunzia Guadagno, Shahrzad Parsa, Sanathana Konugolu Venkata Sek
Published in: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/66062

Cerebral and systemic physiological effects of wearing face masks in young adults.

Author(s): Jonas B. Fischer; Lisa Kobayashi Frisk; Felix Scholkmann; Raquel Delgado-Mederos; Mercedes Mayos; Turgut Durduran
Published in: National Academy of Sciences, Issue 1, 2021, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.5167/uzh-207848

How the heterogeneity of the severely injured brain affects hybrid diffuse optical signals: case examples and guidelines

Author(s): Susanna Tagliabue, Michał Kacprzak, Anna Rey-Perez, Jacinto Baena, Marilyn Riveiro, Federica Maruccia, Jonas B. Fischer, Maria A. Poca, Turgut Durduran
Published in: Neurophotonics, Issue 11, 2024, ISSN 2329-423X
Publisher: SPIE-Intl Soc Optical Eng
DOI: 10.1117/1.nph.11.4.045005

Light-guided dynamic phantom to mimic microvasculature for biomedical applications: an exploration for pulse oximeter

Author(s): Hui Ma, Dario Angelone, Claudia Nunzia Guadagno, Stefan Andersson-Engels, Sanathana Konugolu Venkata Sekar
Published in: Journal of Biomedical Optics, Issue 29, 2025, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.29.s3.s33312

The fNIRS glossary project: a consensus-based resource for functional near-infrared spectroscopy terminology

Author(s): Katharina Stute, Louisa K. Gossé, Samuel Montero-Hernandez, Guy A. Perkins, Meryem A. Yücel, Simone Cutini, Turgut Durduran, Ann-Christine Ehlis, Marco Ferrari, Judit Gervain, Rickson C. Mesquita, Felipe Orihuela-Espina, Valentina Quaresima, Felix Scholkmann, Ilias Tachtsidis, Alessandro Torricelli, Heidrun Wabnitz, Arjun G. Yodh, Stefan A. Carp, Hamid Dehghani, Qianqian Fang, Sergio Fantini, Yo
Published in: Neurophotonics, Issue 12, 2025, ISSN 2329-423X
Publisher: SPIE-Intl Soc Optical Eng
DOI: 10.1117/1.nph.12.2.027801

Fabrication and characterization of multi-biomarker optimized tissue-mimicking phantoms for multi-modal optical spectroscopy

Author(s): Rekha Gautam, Danielle Mac Mahon,Gráinne Eager,Hui Ma,Claudia Nunzia Guadagno,Stefan Andersson-Engels and Sanathana Konugolu Venkata Sekara
Published in: Analyst, 2023, ISSN 0003-2654
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3an00680h

"""Comparison of cerebral metabolic rate of oxygen,blood flow, and bispectral index under general anesthesia"""

Author(s): Susanna Tagliabue, Claus Lindner, Ivette Chochron da Prat, Angela Sanchez-Guerrero, Isabel Serra, Michał Kacprzak , Federica Maruccia, Olga Martinez Silva, Udo M. Weigel, Miriam de Nadal, Maria A. Poca, Turgut Durduran
Published in: Neurophotonics, Issue 10, 2023, ISSN 1539-3704
Publisher: National Library of Medicine
DOI: 10.1117/1.nph.10.1.015006

Solid optical tissue phantom tools based on upconverting nanoparticles for biomedical applications

Author(s): Gokhan Dumlupinar, Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno, Jean S. Matias, Pranav Lanka, Chris K.W. Kho, Stefan Andersson-Engels
Published in: Journal of Biomedical Optics, 2023, ISSN 1083-3668
Publisher: S P I E - International Society for Optical Engineering
DOI: 10.1117/1.jbo.28.3.036004

Pediatric Animal Model of Extracorporeal Cardiopulmonary Resuscitation after Prolonged Circulatory Arrest

Author(s): Madeleine Ball, Sergio Benito, Juliana Pilar Caride, Cristina Ruiz-Herguido, Marta Camprubí-Camprubí, Joan Sanchez-de-Toledo
Published in: Journal of Visualized Experiments, 2024, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/65266

In vivo characterization of the optical and hemodynamic properties of the human sternocleidomastoid muscle through ultrasound-guided hybrid near-infrared spectroscopies

Author(s): Lorenzo Cortese, Pablo Fernández Esteberena, Marta Zanoletti, Giuseppe Lo Presti, Gloria Aranda Velazquez, Sabina Ruiz Janer, Mauro Buttafava, Marco Renna, Laura Di Sieno, Alberto Tosi, Alberto Dalla Mora, Stanislaw Wojtkiewicz, Hamid Dehghani, Sixte de Fraguier, An Nguyen-Dinh, Bogdan Rosinski, Udo M Weigel, Jaume Mesquida, Mattia Squarcia, Felicia A Hanzu, Davide Contini, Mireia Mora Porta, Tur
Published in: Physiological Measurement, Issue 44, 2023, Page(s) 125010, ISSN 0967-3334
Publisher: Institute of Physics Publishing
DOI: 10.1088/1361-6579/ad133a

Performance Assessment of a Commercial Continuous-Wave Near-Infrared Spectroscopy Tissue Oximeter for Suitability for Use in an International, Multi-Center Clinical Trial

Author(s): Lorenzo Cortese, Marta Zanoletti, Umut Karadeniz, Marco Pagliazzi, M. Atif Yaqub, David R. Busch, Jaume Mesquida,Turgut Durduran
Published in: Sensors, 2021, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s21216957

How does obstructive sleep apnea alter cerebral hemodynamics?

Author(s): Clara Gregori-Pla, Peyman Zirak, Gianluca Cotta, Pau Bramon, Igor Blanco, Isabel Serra, Anna Mola, Ana Fortuna, Jordi Solà-Soler, Beatriz F Giraldo Giraldo, Turgut Durduran, Mercedes Mayos
Published in: Sleep, 2023, ISSN 1539-3704
Publisher: National Library of Medicine
DOI: 10.1093/sleep/zsad122

Transcranial optical monitoring for detecting intracranial pressure alterations in children with benign external hydrocephalus: a proof-of-concept study

Author(s): Maruccia, F; Tagliabue, S; Fischer, JB; Kacprzak, M; Perez-Hoyos, S; Rosas, K; Alvarez, ID; Sahuquillo, J; Durduran, T; Poca, MA
Published in: Neurophotonics, Issue 9, 2022, ISSN 0090-3132
Publisher: National Library of Medicine
DOI: 10.1117/1.nph.9.4.045005

Recipes for diffuse correlation spectroscopy instrument design using commonly utilized hardware based on targets for signal-to-noise ratio and precision

Author(s): Lorenzo Cortese, Giuseppe Lo Presti, Marco Pagliazzi, Davide Contini, Alberto Dalla Mora, Hamid Dehghani, Fabio Ferri, Jonas B. Fischer, Martina Giovannella, Fabrizio Martelli, Udo M. Weigel, Stanislaw Wojtkiewicz, Marta Zanoletti, Turgut Durduran
Published in: Biomedical Optics Express, Issue 12/6, 2021, Page(s) 3265, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.423071

Neural encoding of auditory rhythm beyond cortical auditory areas before the age of term

Author(s): Ali Rajabi Mashhadi, Fabrice Wallois, Mohammadreza Edalati, Florence Levé, Alexandros Stamatiadis, Christelle Chazal, Laurel Trainor, Sahar Moghimi
Published in: iScience, Issue 28, 2025, Page(s) 113028, ISSN 2589-0042
Publisher: Elsevier BV
DOI: 10.1016/j.isci.2025.113028

Near-infrared diffuse optical characterization of human thyroid using ultrasound-guided hybrid time-domain and diffuse correlation spectroscopies

Author(s): Pablo Fernández Esteberena, Lorenzo Cortese, Marta Zanoletti, Giuseppe Lo Presti, Gloria Aranda Velazquez, Sabina Ruiz Janer, Mauro Buttafava, Marco Renna, Laura Di Sieno, Alberto Tosi, Alberto Dalla Mora, Stanislaw Wojtkiewicz, Hamid Dehghani, Sixte de Fraguier, An Nguyen-Dinh, Bogdan Rosinski, Udo M. Weigel, Dibya J. Sarangi, Mattia Squarcia, Felicia A. Hanzu, Davide Contini, Mireia Mora Porta,
Published in: Biomedical Optics Express, Issue 15, 2024, Page(s) 7035, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.538141

Transcranial, noninvasive evaluation of the potential misery perfusion during hyperventilation therapy of traumatic brain injury patients

Author(s): Susanna Tagliabue, Michal Kacprzak, Isabel Serra, Federica Maruccia, Jonas Benedikt Fischer, Marilyn Riveiro, Anna Rey-Perez, Lourdes Exposito, Claus Lindner, Marcelino Báguena, Turgut Durduran, Maria A. Poca
Published in: Journal of neurotrauma, 2023, ISSN 0090-3132
Publisher: National Library of Medicine
DOI: 10.1089/neu.2022.0419

Conference proceedings (6)

Can LIDARs address skin color bias?

Author(s): Sanathana Konugolu Venkata Sekar, Claudia Nunzia Guadagno, Stefan Andersson-Engels
Published in: Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN), 2025, Page(s) JS4A.53
Publisher: Optica Publishing Group
DOI: 10.1364/translational.2024.js4a.53

Exploring pulse waveform characteristic changes due to intracranial compliance in hydrocephalus patients

Author(s): Carolina Fajardo Vega, Susanna Tagliabue, Jonas B. Fischer, Monica Torrecilla Vall-llossera, Gemma Piella, Diego F. López, Katiuska Rosas, Maria A. Poca, Juan Sahuquillo, Turgut Durduran
Published in: Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN), 2025, Page(s) JS4A.32
Publisher: Optica Publishing Group
DOI: 10.1364/translational.2024.js4a.32

Exploring intracranial pressure variations through transcranial hybrid diffuse optical measurements in benign external hydrocephalus

Author(s): S. Tagliabue, F. Maruccia, V. Parfentyeva, J. B. Fischer, K. Rosas, G. Piella, I. Delgado Alvarez, M. Baguena, P. Cano, M. A. Poca, T. Durduran
Published in: Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN), 2025, Page(s) BTu4C.6
Publisher: Optica Publishing Group
DOI: 10.1364/brain.2024.btu4c.6

Integrated Multi-Sensor Board for Quality Assurance and Laser Safety in Near-Infrared Spectroscopies

Author(s): Yaqub M.A.; Zanoletti M.; Cortese L.; Karadeniz U.; Ghouse A.; Weigel U.M.; Fischer J.B.; Durduran T.
Published in: 2022
Publisher: Optics InfoBase Conference Papers

Investigating cerebral biomarkers of neonates in risky periods of cardiac repair surgery with diffuse optical monitor

Author(s): Can O.M.; Patil N.; Tresanchez G.; Vazquez D.C.; Rivas A.; Herguido C.R.; Behera A.; Frisk L.K.; Fischer J.; Yaqub M.A.; Camprubí M.; Sanchez de Toledo J.; Durduran T.
Published in: 2024
Publisher: Optical Tomography and Spectroscopy, OT and S 2024 in Proceedings Optica Biophotonics Congress: Biomedical Optics 2024, Translational, Microscopy, OCT, OTS, BRAIN - Part of Optica Biophotonics Congress: Biomedical Optics

Muscle Hemodynamic and Metabolic Response to Blood Flow Restriction

Author(s): Manish Verma, Umut Karadeniz, M. Atif Yaqub, Blai Ferrer-Uris, Albert Busquets, Nathan Mbuyamba, Sjors Arnold, Raquel Martínez-Reviejo, Turgut Durduran
Published in: Optica Biophotonics Congress: Biomedical Optics 2024 (Translational, Microscopy, OCT, OTS, BRAIN), 2025, Page(s) JM4A.20
Publisher: Optica Publishing Group
DOI: 10.1364/translational.2024.jm4a.20

Non-peer reviewed articles (1)

Hybrid Heterogeneous Phantoms for Biomedical Applications: a demonstration to dosimetry validation

Author(s): Ghauri, Muhammad Daniyal; Susnjar, Stefan; Guadagno, Claudia Nunzia; Bhattacharya, Somdatta; Thomasson, Björn; Swartling, Jjohannes, Rekha Gautam, Stefan Andersson-Engels and Sanathana Konugolu Venkata Sekar
Published in: Optica Publishing Group, 2024, ISSN 1084-7529
Publisher: Optical Society of America
DOI: 10.1364/opticaopen.24713385.v1