Printing spatially and temporally defined boundaries to direct the self-organization of cells and cellular aggregates to engineer functional tissues

Project Information

4D-BOUNDARIES

Grant agreement ID: 101019344

DOI

10.3030/101019344

EC signature date 24 July 2021

Start date 1 September 2021

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 703 115,00

EU contribution

€ 2 703 115,00

Coordinated by

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Bioassembly of Region‐Specific Fibrocartilage Microtissues to Engineer Zonally Defined Meniscal Grafts

Author(s): Gabriela S. Kronemberger, Kaoutar Chattahy, Francesca D. Spagnuolo, Aliaa S. Karam, Daniel J. Kelly
Published in: Advanced Healthcare Materials, Issue 14, 2025, Page(s) e02208, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202502208

The maturation state and density of human cartilage microtissues influence their fusion and development into scaled-up grafts

Author(s): Francesca D. Spagnuolo, Gabriela S. Kronemberger, Kyle J. Storey, Daniel J. Kelly
Published in: Acta Biomaterialia, Issue 194, 2025, Page(s) 109-121, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2025.01.024

Cell-only bioprinting of articular cartilage progenitor cells within a physically constraining support bath to engineer structurally organized grafts

Author(s): Aliaa S. Karam, Gabriela S. Kronemberger, Kaoutar Chattahy, Daniel J. Kelly
Published in: Bioactive Materials, Issue 59, 2026, Page(s) 251-265, ISSN 2452-199X
Publisher: Elsevier BV
DOI: 10.1016/j.bioactmat.2025.12.013

Rapidly Degrading Hydrogels to Support Biofabrication and 3D Bioprinting Using Cartilage Microtissues

Author(s): Gabriela S. Kronemberger, Francesca D. Spagnuolo, Aliaa S. Karam, Kaoutar Chattahy, Kyle J. Storey, Daniel J. Kelly
Published in: ACS Biomaterials Science & Engineering, 2024, ISSN 2373-9878
Publisher: American Chemical Society
DOI: 10.1021/acsbiomaterials.4c00819

Restoring articular cartilage: insights from structure, composition and development

Author(s): Alba Pueyo Moliner, Keita Ito, Frank Zaucke, Daniel J. Kelly, Mylène de Ruijter, Jos Malda
Published in: Nature Reviews Rheumatology, Issue 21, 2025, Page(s) 291-308, ISSN 1759-4790
Publisher: Nature Publishing Group
DOI: 10.1038/s41584-025-01236-7