Understanding the Biology of Human Enteroendocrine Cells

Project Information

GutHormones

Grant agreement ID: 101020405

DOI 10.3030/101020405

EC signature date 15 July 2021

Start date 1 October 2021

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 733 150,00

EU contribution € 2 733 150,00

Coordinated by

F. HOFFMANN-LA ROCHE AG
Switzerland

Publications

Peer reviewed articles (2)

Mapping prohormone processing by proteases in human enteroendocrine cells using genetically engineered organoid models

Author(s): Joep Beumer, Julia Bauzá-Martinez, Tim S. Veth, Veerle Geurts, Charelle Boot, Hannah Gilliam-Vigh, Steen S. Poulsen, Filip K. Knop, Wei Wu and Hans Clevers
Published in: PNAS, Issue Nov 15; 119(46), 2022, Page(s) 1-11, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2212057119

Differentiation and CRISPR-Cas9-mediated genetic engineering of human intestinal organoids

Author(s): Adriana Martinez-Silgado, Fjodor A. Yousef Yengej, Jens Puschhof,Veerle Geurts, Charelle Boot, Maarten H. Geurts, Maarten B. Rookmaaker, Marianne C. Verhaar, Joep Beumer, and Hans Clevers
Published in: Star Protocols, Issue Volume 3, Issue 3, 16 September, 2022, Page(s) 1-11, ISSN 2666-1667
Publisher: Cell Press
DOI: 10.1016/j.xpro.2022.101639