Structure and mechanism of respiratory chain molecular machines

Project description

Solving the mystery of mitochondrial respiration

Mitochondria are considered the powerhouse of eukaryotic cells, facilitating the production of most of the required energy in the form of ATP. Enzymes of the respiratory chain are responsible for converting the energy released from catabolic processes within the cell to ATP. The EU-funded RESPICHAIN project will focus on complex I, the largest respiratory enzyme that consists of 45 subunits. Researchers will investigate the mechanism of energy transduction carried out by complex I and delineate its structure. The work will provide fundamental knowledge in biology and insight into the aetiology of many human diseases.

Fields of science

• natural sciences › biological sciences › microbiology › bacteriology
• natural sciences › biological sciences › genetics › nucleotides
• medical and health sciences › basic medicine › physiology › homeostasis
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › enzymes

Programme(s)

• H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC) Main Programme

Topic(s)

• ERC-2020-ADG - ERC ADVANCED GRANT

Call for proposal

ERC-2020-ADG

See other projects for this call

Funding Scheme

ERC-ADG - Advanced Grant

Host institution

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA

Net EU contribution

€ 1 781 133,00

Address

Am Campus 1
3400 Klosterneuburg
Austria

Region

Niederösterreich › Wiener Umland/Nordteil

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00

Beneficiaries (1)

INSTITUTE OF SCIENCE AND TECHNOLOGY AUSTRIA

Austria

Net EU contribution

€ 1 781 133,00

Address

Am Campus 1
3400 Klosterneuburg

Region

Niederösterreich › Wiener Umland/Nordteil

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00