Functional Glycomics Through Chemoenzymatic Synthesis

Project Information

SWEETPROMISE

Grant agreement ID: 101020769

DOI

10.3030/101020769

EC signature date 19 November 2021

Start date 1 January 2022

End date 31 December 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

UNIVERSITEIT UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Non-peer reviewed articles (2)

Glycoproteomics-compatible MS/MS-based quantification of glycopeptide isomers

Author(s): Joshua C.L. Maliepaard, J. Mirjam A. Damen, Geert-Jan P.H. Boons, Karli R. Reiding
Published in: bioRxiv, Issue 31 january 2023, 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.01.31.526390

Potential impacts of prolonged absence of influenza virus circulation on subsequent epidemics

Author(s): Simon P. J. de Jong, Zandra C. Felix Garza, Joseph C. Gibson, Alvin X. Han, Sarah van Leeuwen, Robert P. de Vries, Geert-Jan Boons, Marliek van Hoesel, Karen de Haan, Laura E. van Groeningen, Katina D. Hulme, Hugo D. G. van Willigen, Elke Wynberg, Godelieve J. de Bree, Amy Matser, Margreet Bakker, Lia van der Hoek, Maria Prins, Neeltje A. Kootstra, Dirk Eggink, Brooke E. Nichols, Menno D. de Jong,
Published in: medRxiv, Issue 16 November 2022, 2024, Page(s) 16 November 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.02.05.22270494

Peer reviewed articles (8)

Glycoproteomics-Compatible MS/MS-Based Quantification of Glycopeptide Isomers

Author(s): Joshua C.L. Maliepaard; J. Mirjam A. Damen; Geert-Jan P.H. Boons; Karli R. Reiding
Published in: Anal. Chem., Issue Year 2023 Volume 95 Issue 25, 2023, Page(s) 9605-9614, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.3c01319

Sialoglycan binding triggers spike opening in a human coronavirus

Author(s): Matti F. Pronker, Robert Creutznacher, Ieva Drulyte, Ruben J. G. Hulswit, Zeshi Li, Frank J. M. van Kuppeveld, Joost Snijder, Yifei Lang, Berend-Jan Bosch, Geert-Jan Boons, Martin Frank, Raoul J. de Groot, Daniel L. Hurdiss
Published in: Nature, Issue 624, 2023, Page(s) 201-206, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-023-06599-z

A Biomimetic Synthetic Strategy can Provide Keratan Sulfate I and II Oligosaccharides with Diverse Fucosylation and Sulfation Patterns

Author(s): Yunfei Wu, Gerlof Bosman, Digantkumar Chapla, Chin Huang, Kelley Moremen, Robert de Vries, Geert-Jan Boons
Published in: J. Am. Chem. Soc., Issue 146, 2024, Page(s) 9230-9240, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.26434/chemrxiv-2024-55x0s

Chemoenzymatic Synthesis of Keratan Sulfate Oligosaccharides Using UDP-Galactose-6-aldehyde To Control Sulfation at Galactosides

Author(s): Yunfei Wu, Gerlof P. Bosman, Gaël M. Vos, Elif Uslu, Digantkumar Chapla, Chin Huang, Kelley W. Moremen, Geert-Jan Boons
Published in: Organic Letters, Issue 26, 2024, Page(s) 8272-8277, ISSN 1523-7060
Publisher: American Chemical Society
DOI: 10.1021/acs.orglett.4c02899

Exploiting Substrate Specificities of 6-<i>O</i>-Sulfotransferases to Enzymatically Synthesize Keratan Sulfate Oligosaccharides

Author(s): Yunfei Wu, Gaël M. Vos, Chin Huang, Digantkumar Chapla, Anne L. M. Kimpel, Kelley W. Moremen, Robert P. de Vries, Geert-Jan Boons
Published in: JACS Au, Issue 3, 2023, Page(s) 3155-3164, ISSN 2691-3704
Publisher: American Chemical Society
DOI: 10.1021/jacsau.3c00488

Determinants of epidemic size and the impacts of lulls in seasonal influenza virus circulation

Author(s): Simon P. J. de Jong, Zandra C. Felix Garza, Joseph C. Gibson, Sarah van Leeuwen, Robert P. de Vries, Geert-Jan Boons, Marliek van Hoesel, Karen de Haan, Laura E. van Groeningen, Katina D. Hulme, Hugo D. G. van Willigen, Elke Wynberg, Godelieve J. de Bree, Amy Matser, Margreet Bakker, Lia van der Hoek, Maria Prins, Neeltje A. Kootstra, Dirk Eggink, Brooke E. Nichols, Alvin X. Han, Menno D. de Jong,
Published in: Nature Communications, Issue 15, 2024, Page(s) 591, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-44668-z

Chemoenzymatic synthesis of human natural killer-1-containing glycans and application as serum antibodies probes

Author(s): Mehman Bunyatov, Margreet A. Wolfert, Lin Liu, Ruth Huizinga, Marco W. J. Schreurs, Bart C. Jacobs, Geert-Jan Boons
Published in: Nature Synthesis, Issue 3, 2024, Page(s) 85-98, ISSN 2731-0582
Publisher: Nature Publishing Group
DOI: 10.1038/s44160-023-00394-4

Sialic acid O-acetylation patterns and glycosidic linkage type determination by ion mobility-mass spectrometry

Author(s): Gaёl M. Vos, Kevin C. Hooijschuur, Zeshi Li, John Fjeldsted, Christian Klein, Robert P. de Vries, Javier Sastre Toraño, Geert-Jan Boons
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-42575-x

Other (2)

Synthetic HNK-1 containing glycans provide insight into binding properties of serum antibodies from MAG-neuropathy patients

Author(s): M. Bunyatov, M.A. Wolfert, R. Huizinga, M. Schreurs, B.C. Jacobs, G.J. Boons
Published in: bioRxiv, Issue 25 July 2022, 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.07.25.501369

Exploiting substrate specificities of 6-O-sulfotransferases to enzymatically synthesize keratan sulfate oligosaccharides

Author(s): Y. Wu, G. Vos, C. Huang, D. Chapla, A.L.M. Kimpel, K.W. Moremen, R.P. de Vries, G.J. Boons
Published in: bioRxiv, Issue 20 August 2023, 2023, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.08.20.554027