Project description
Tissue-engineering microfluidic device for drug development
3D cell cultures for medical research and regenerative medicine are critical for more accurate and ethical medical innovations. Tissue-engineered scaffold-free 3D models that mimic functional characteristics of native tissues support biomarker search, drug development and toxicology studies while providing an alternative to animal use in drug testing and research. Funded by the Marie Skłodowska-Curie Actions programme, the SMD-SPH project is developing a microphysiological system comprising a 3D cell culture model with controllable perfusion for continuous contact with growth factors, with the aim of creating a functional native tissue and monitoring the crucial physiological parameters. For the first time, human adipose tissue-derived stem cells will be used to build adipose tissue as a scalable microphysiological system.
Fields of science
- natural sciencesphysical sciencesclassical mechanicsfluid mechanicsmicrofluidics
- medical and health sciencesmedical biotechnologytissue engineering
- medical and health sciencesmedical biotechnologycells technologiesstem cells
- engineering and technologyother engineering and technologiesmicrotechnologyorgan on a chip
- medical and health sciencesbasic medicinetoxicology
Programme(s)
Funding Scheme
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
Coordinator
75015 Paris
France
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