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Development of scalable microfluidic device for drug testing using humanized adipose tissue spheroids

Project description

Tissue-engineering microfluidic device for drug development

3D cell cultures for medical research and regenerative medicine are critical for more accurate and ethical medical innovations. Tissue-engineered scaffold-free 3D models that mimic functional characteristics of native tissues support biomarker search, drug development and toxicology studies while providing an alternative to animal use in drug testing and research. Funded by the Marie Skłodowska-Curie Actions programme, the SMD-SPH project is developing a microphysiological system comprising a 3D cell culture model with controllable perfusion for continuous contact with growth factors, with the aim of creating a functional native tissue and monitoring the crucial physiological parameters. For the first time, human adipose tissue-derived stem cells will be used to build adipose tissue as a scalable microphysiological system.

Call for proposal

H2020-MSCA-IF-2020
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Coordinator

EDEN TECH
Address
11 Rue De Lourmel
75015 Paris
France
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 196 707,84