Project description
Novel nanomaterials for bioimaging
Organic room-temperature phosphorescence materials (ORTPs) exhibit high luminescence and find application in high-resolution imaging. Metal-free ORTP materials have become a promising choice because they are inexpensive and environmentally friendly. The key objective of the EU-funded FUNCrystals project is to develop ORTP nanocrystals with expanded applications in microscopy. Researchers will establish a scalable method for nanoscale ORTP production and investigate the optical properties of the generated compounds as well as their spatiotemporal distribution and contrast in cells. The project will pave the way towards the formation of ORTP-based nanoprobes for bioimaging applications.
Objective
Recently, organic room-temperature phosphorescence materials (ORTPs) have gathered tremendous interest due to their high brightness and ultra-long lifetime (ULL) features, and ORTPs are useful in many advanced applications, including optoelectronics, bioimaging(BI), and photomedicine. However, at this early stage of development, processing of nanoform ORTPs and scalable synthesis lag behind other forms of ORTPs, leaving the chances for many applications nearly uncharted. Thus, the FUNCrystals project aims to develop functional ORTP nanocrystals (NCs) for two-photon phosphorescence lifetime imaging microscopy (2P-PLIM) BI applications. In particular, the project proposes 3 main activities that capitalize on the strength of the proposed experienced researcher and the host research group (Prof. Clemens Kaminski), in ORTP-NCs synthesis and 2P-PLIM usage. 1.Develop a synthesis process to control the size and shape of ORTP-NCs with high emission quantum yield (QY) and ULL. 2.Investigate the nonlinear optical (NLO) properties and biocompatibility analysis of ORTP-NCs. 3.Use the ORTP-NCs as nanoprobes in the 2P-PLIM to capture the high spatiotemporal and high contrast image in the primary Epithelial cell lines. The expected results will exploit the size and shape-dependent properties of the ORTP-NCs, aiming to demonstrate property performances that can elicit commercial interest in potential nanoprobes for 2P-PLIM bioimaging applications. This project's success will make a substantial contribution to one of the European Union's main concerns on developing nanotechnologies and advanced materials. Overall, this proposed multidisciplinary project brings benefits to both the applicant and the host institution(University of Cambridge) in terms of mutual knowledge transfer, joint publications, new collaborations, networking actions, and personal career development of the researcher as well as increased public awareness about research resulting from the ambitious outreach actions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences electromagnetism and electronics optoelectronics
- natural sciences physical sciences optics microscopy
- engineering and technology nanotechnology nano-materials nanocrystals
You need to log in or register to use this function
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
-
H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
See all projects funded under this programme -
H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
See all projects funded under this programme
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
See all projects funded under this funding scheme
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
See all projects funded under this callCoordinator
Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
CB2 1TN CAMBRIDGE
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.