Skip to main content

Immunological and Microbiota Priming of the Response to Infection

Project description

Role of gut microbiota in immune system development

The gut microbiota is a complex of intestinal microorganisms acquired in early life, which participate in the development of the immune system. Recent research revealed that a transient intestinal inflammatory state, the ‘weaning reaction’, occurs in mice in early life in response to rapid diversification of the gut microbiota. The microbiota and its metabolites in this weaning state induce a sub-type of intestine T regulatory cells, which regulate immune reactivity for the rest of one’s life. The EU-funded IMPRINT project will elucidate the role of the gut microbiota in the immune system in early life and its significance for susceptibility to infection and immunopathologies, such as allergies and colitis, later in life.


Net EU contribution
€ 196 707,84
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15

See on map

Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00