Objective
Microelectronic medical implants with superior performance are needed to improve quality of life for patients. For neuroelectronic applications, this will be enabled through miniaturisation of large numbers of high-density electrodes in bio-mimetic packages. The leading solution is to use ultra-thin silicon chips (UTCs) embedded in flexible polymers with small flexible ribbon cables. However, this technology creates a unique challenge of maintaining sufficient hermeticity, biocompatibility and biostability for decades-long implantation without the use of bulky, rigid glass/Ti boxes. The primary aim of THINPAC (Thin Hermetic Implantables using Novel Packaging of Active Chips) is to realize a robust technology platform for ultra-thin flexible hermetic packaging of UTCs using alternating layers of ceramic nanofilms and polyimide. Innovation beyond existing fabrication technology is needed (i.e. bonding for higher yield, thin-film noble metal patterns over chip edge topography, and hermetic connector strategies). THINPAC will aim to develop these technologies by solving remaining fabrication issues and in-depth in vitro evaluation of the developed technology to ensure long term hermeticity, biostability, and flexibility. New testing strategies will be developed towards highly reliable test protocols for real-time and accelerated testing to mimic long term evaluation of implants. Implant development is a highly multidisciplinary activity and in vivo testing in animals is indispensable. Discussion with medical people and initial tests with dummy devices are essential from the start of the project to avoid less suitable medical devices. Finally, functional probes for implantation into peripheral nerves will be fabricated and fully characterized in rats for foreign body reaction and electrophysiology. With this project, we aim to mature a technology platform for advanced implant fabrication and for the first time make it viable for clinical translation into humans.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences astronomy planetary sciences planetary geology
- natural sciences chemical sciences polymer sciences
- engineering and technology materials engineering
- natural sciences chemical sciences inorganic chemistry metalloids
- medical and health sciences medical biotechnology implants
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-IF-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
3001 Leuven
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.