To achieve the objectives of both research lines, we have conducted an intensive 9-month longitudinal intervention study among 125 romantic couples. This study examined how automatic partner attitudes relate to relationship experiences and affect relationship behaviours through videotaped interactions, daily, weekly, and monthly reports, while also testing the effectiveness of two interventions that target such attitudes. The longitudinal assessments revealed that automatic partner attitudes fluctuated based on the accumulation of both positive and negative relationship experiences over time, particularly those charged with strong affect. This pattern suggests that automatic partner attitudes may reflect one’s history of relationship experiences, and perhaps more accurately than self-reports. Moreover, automatic partner attitudes also uniquely predicted a variety of behaviours critical for relationship functioning and well-being, even when self-reported attitudes did not. Specifically, automatic partner attitudes more strongly predicted spontaneous behaviours exhibited in videotaped conversations and in daily diaries, as well as more general behaviours in situations where opportunities for effortful processing were limited. Importantly, these behavioural effects appeared to have downstream consequences for satisfaction: more positive automatic partner attitudes were associated with more functional (and less dysfunctional) behaviours toward the partner, which in turn predicted higher relationship satisfaction over time. Then, we implemented two experimental manipulations to test the causal role of automatic partner attitudes: a relational-expansion procedure to examine whether engaging in new and exciting activities with the partner can enhance automatic partner attitudes and in turn improve relationship functioning and well-being; and a mindfulness training protocol to examine whether such training enables participants to become more aware of their automatic partner attitudes and better equipped to accept and regulate them and in turn promote relationship quality. While both interventions appeared to improve relationship satisfaction, they did not seem to affect automatic partner attitudes or behaviours. That is, couples benefited from both the relational-expansion procedure and mindfulness training, but these effects were not explained by more positive attitudes or greater awareness and regulation of automatic attitudes. Overall, the findings suggest that automatic partner attitudes play a central role in romantic relationships. However, interventions designed to enhance or better regulate such attitudes proved challenging, indicating that longer or more intensive approaches may be needed to effectively leverage automatic partner attitudes for relationship well-being. These results have been disseminated through presentations at conferences, invited talks, and local events. A theoretical review that critically discusses evidence on the sources and antecedents of automatic partner attitudes in close relationships, identifies unanswered questions, and proposes a comprehensive agenda for future research, has also been published in open access.