Psychiatric Ratings using Intermediate Stratified Markers 2

Project Information

PRISM 2

Grant agreement ID: 101034377

DOI 10.3030/101034377

Project closed

EC signature date 19 May 2021

Start date 1 June 2021

End date 30 November 2024

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 7 894 553,69

EU contribution € 3 980 906,25

Coordinated by

RIJKSUNIVERSITEIT GRONINGEN
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (4)

First electronic bulletin online
Video explaining new knowledge on transdiagnostic approach
Brochure to inform in brief about PRISM 2 for participants involved in the clinical study
Go-live of updated public project website

Golive of updated public project website

Documents, reports (6)

Patient event
Summary report on major publications/findings
Summary report on the success of the chosen communication channels (ECNP)
Summary report on Masterclasses
Data Management Plan
Dissemination and Communication plan

Demonstrators, pilots, prototypes (1)

Scientific Advice Letter on the validation of biomarkers

Publications

Peer reviewed articles (18)

Social dysfunction is associated with altered facial emotion neural processing across diverse neuropsychiatric disorders

Author(s): S. Braak, G. Bakker, T. Su, Y. Pijnenburg, A.V. Campos, A. De la Torre-Luque, A. Beckenstrom, A. Malik, G.R. Dawson, H. Marston, J. Alvarez-Linera, J.L. Ayuso-Mateos, C. Arango, M.J. Van Tol, N. Van der Wee, M.J. Kas, M. Aghajani, B.W.J.H. Penninx
Published in: Neuroscience Applied, Issue 3, 2024, Page(s) 103977, ISSN 2772-4085
Publisher: Elsevier BV
DOI: 10.1016/j.nsa.2024.103977

Default mode network dynamics: An integrated neurocircuitry perspective on social dysfunction in human brain disorders

Author(s): Mirthe Ronde, Eddy A. van der Zee, Martien J.H. Kas
Published in: Neuroscience & Biobehavioral Reviews, Issue 164, 2024, Page(s) 105839, ISSN 0149-7634
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.neubiorev.2024.105839

The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case–control study

Author(s): Lucia Sideli, Monica Aas, Diego Quattrone, Daniele La Barbera, Caterina La Cascia, Laura Ferraro, Luis Alameda, Eva Velthorst, Giulia Trotta, Giada Tripoli, Adriano Schimmenti, Andrea Fontana, Charlotte Gayer-Anderson, Simona Stilo, Fabio Seminerio, Crocettarachele Sartorio, Giovanna Marrazzo, Antonio Lasalvia, Sarah Tosato, Ilaria Tarricone, Domenico Berardi, Giuseppe D’Andrea, null null, Silvi
Published in: Social Psychiatry and Psychiatric Epidemiology, Issue 58, 2023, Page(s) 1573-1580, ISSN 0933-7954
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00127-023-02513-0

Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis

Author(s): Bas-Hoogendam et al.
Published in: American Academy of Child and Adolescent Psychiatry, 2022, ISSN 1527-5418
Publisher: Elsevier Inc
DOI: 10.1016/j.jaac.2022.04.023

Analysis of common genetic variation across targets of microRNAs dysregulated both in ASD and epilepsy reveals negative correlation

Author(s): Stella et al.
Published in: Frontiers in Genetics, Issue 14: 1072563, 2023, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2023.1072563

Is there such a thing as gambling dual disorder? Preliminary evidence and clinical profiles

Author(s): Néstor Szerman, Ignacio Basurte-Villamor, Pablo Vega, Beatriz Mesías, José Martínez-Raga, Francisco Ferre, Celso Arango
Published in: European Neuropsychopharmacology, Issue 66, 2024, Page(s) 78-91, ISSN 0924-977X
Publisher: Elsevier BV
DOI: 10.1016/j.euroneuro.2022.11.010

The aperiodic exponent of neural activity varies with vigilance state in mice and men

Author(s): Freja Gam Østergaard, Brenda W. J. H. Penninx, Neetha Das, Celso Arango, Nic van der Wee, Inge Winter-van Rossum, Jose Luis Ayuso-Mateos, Gerard R. Dawson, Hugh Marston, Martien J. H. Kas
Published in: PLOS ONE, Issue 19, 2024, Page(s) e0301406, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0301406

Theory of Mind and social functioning among neuropsychiatric disorders: A transdiagnostic study

Author(s): S. Braak, T. Su, W. Krudop, Y.A.L. Pijnenburg, L.M. Reus, N. van der Wee, A.C. Bilderbeck, G.R. Dawson, I. Winter- van Rossum, A. Vieira Campos, C. Arango, I.M.J. Saris, M.J. Kas, B.W.J.H. Penninx
Published in: European Neuropsychopharmacology, Issue Volume 64, 2022, Page(s) Pages 19-29, ISSN 0924-977X
Publisher: Elsevier BV
DOI: 10.1016/j.euroneuro.2022.08.005

Finding the Right Setting for the Right Treatment During the Acute Treatment of Individuals with Schizophrenia: A Narrative Review and Clinical Practice Guideline

Author(s): Christoph Correll, Celso Arango, Andrea Fagiolini, Giulia Giordano, Stefan Leucht, Gonzalo Salazar de Pablo
Published in: Neuropsychiatric Disease and Treatment, Issue Volume 20, 2024, Page(s) 1293-1307, ISSN 1178-2021
Publisher: Neuropsychiatris Disease and Treatment
DOI: 10.2147/ndt.s459450

Child maltreatment should be a priority for public mental health interventions

Author(s): Celso Arango
Published in: European Archives of Psychiatry and Clinical Neuroscience, Issue 273, 2023, Page(s) 1007-1008, ISSN 0940-1334
Publisher: Dr. Dietrich Steinkopff Verlag
DOI: 10.1007/s00406-023-01643-5

Mapping gray and white matter volume abnormalities in early-onset psychosis: an ENIGMA multicenter voxel-based morphometry study

Author(s): Shuqing Si, Anbreen Bi, Zhaoying Yu, Cheryl See, Sinead Kelly, Sonia Ambrogi, Celso Arango, Inmaculada Baeza, Nerisa Banaj, Michael Berk, Josefina Castro-Fornieles, Benedicto Crespo-Facorro, Jacob J. Crouse, Covadonga M. Díaz-Caneja, Anne-Kathrin Fett, Adriana Fortea, Sophia Frangou, Benjamin I. Goldstein, Ian B. Hickie, Joost Janssen, Kody G. Kennedy, Lydia Krabbendam, Marinos Kyriakopoulos, Bra
Published in: Molecular Psychiatry, Issue 29, 2024, Page(s) 496-504, ISSN 1359-4184
Publisher: Nature Publishing Group
DOI: 10.1038/s41380-023-02343-1

Delphi panel to obtain clinical consensus about using long-acting injectable antipsychotics to treat first-episode and early-phase schizophrenia: treatment goals and approaches to functional recovery

Author(s): Celso Arango, Andrea Fagiolini, Philip Gorwood, John M. Kane, Sergio Diaz-Mendoza, Navdeep Sahota, Christoph U. Correll
Published in: BMC Psychiatry, Issue 23, 2023, ISSN 1471-244X
Publisher: BioMed Central
DOI: 10.1186/s12888-023-04928-0

Examining the association between exposome score for schizophrenia and cognition in schizophrenia, siblings, and healthy controls: Results from the EUGEI study

Author(s): Laura Fusar-Poli, Thanavadee Prachason, Gamze Erzin, Lotta-Katrin Pries, Natascia Brondino, Pierluigi Politi, Philippe Delespaul, Gunter Kenis, Jurjen J Luykx, Bochao D Lin, Alexander L Richards, Berna Akdede, Tolga Binbay, Vesile Altınyazar, Berna Yalınçetin, Güvem Gümüş-Akay, Burçin Cihan, Haldun Soygür, Halis Ulaş, Eylem Şahin Cankurtaran, Semra Ulusoy Kaymak, Marina M Mihaljevic, Sa
Published in: Psychiatry Research, Issue Volume 323, 2023, Page(s) 115184, ISSN 0165-1781
Publisher: Elsevier BV
DOI: 10.1016/j.psychres.2023.115184

Comorbid physical health burden of serious mental health disorders in 32 European countries

Author(s): Dennis Wienand, Lena I Wijnen, Daniel Heilig, Christoph Wippel, Celso Arango, Gitte M Knudsen, Guy M Goodwin, Judit Simon
Published in: BMJ Mental Health, Issue 27, 2025, Page(s) e301021, ISSN 2755-9734
Publisher: BMJ Mental Health
DOI: 10.1136/bmjment-2024-301021

Social dysfunction relates to shifts within socioaffective brain systems among Schizophrenia and Alzheimer's disease patients

Author(s): Simon Braak, Brenda WJH Penninx, Tanja Su, Yolande Pijnenburg, Daphne Nijland, Alba Vieira Campos, Alejandro de la Torre-Luque, Ilja M.J. Saris, Lianne M. Reus, Amy Christine Beckenstrom, Asad Malik, Gerard R. Dawson, Hugh Marston, Juan Alvarez-Linera, Jose-Luis L. Ayuso-Mateos, Celso Arango, Nic van der Wee, Martien J. Kas, Moji Aghajani
Published in: European Neuropsychopharmacology, Issue 86, 2024, Page(s) 1-10, ISSN 0924-977X
Publisher: Elsevier BV
DOI: 10.1016/j.euroneuro.2024.05.004

Forceps minor control of social behaviour

Author(s): Franziska Stoller, Eleanor Hinds, Tudor Ionescu, Elmira Khatamsaz, Hugh M. Marston, Bastian Hengerer
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-81930-w

Towards a consensus roadmap for a new diagnostic framework for mental disorders

Author(s): Martien J.H. Kas, Steven Hyman, Leanne M. Williams, Diego Hidalgo-Mazzei, Quentin J.M. Huys, Matthew Hotopf, Bruce Cuthbert, Cathryn M. Lewis, Livia J. De Picker, Paris A. Lalousis, Amit Etkin, Gemma Modinos, Hugh M. Marston
Published in: European Neuropsychopharmacology, Issue 90, 2024, Page(s) 16-27, ISSN 0924-977X
Publisher: Elsevier BV
DOI: 10.1016/j.euroneuro.2024.08.515

Social Dysfunction and Neural Processing of Emotional Valence Across Depressive and Anxiety Disorders

Author(s): Simon Braak, Geor Bakker, Tanja Su, Channah Osinga, Laura Nawijn, Marie-Jose van Tol, Nic J. A. Van der Wee, Yolande Pijnenburg, Brenda W. J. H. Penninx
Published in: Depression and Anxiety, Issue 2024, 2024, ISSN 1091-4269
Publisher: John Wiley & Sons Inc.
DOI: 10.1155/2024/8564344

Conference proceedings (2)

Social dysfunction relates to transdiagnostic shifts within socioaffective brain systems among neuropsychiatric disorders

Author(s): S. Braak, B. Penninx, T. Su, Y. Pijnenburg, D. Nijland, A. Vieira Campos, A. De la Torre-Luque, I.M.J. Saris, L.M. Reus, A. Beckenstrom, A. Malik, G.R. Dawson, H. Marston, J. Linera, J.L.L. Ayuso-Mateos, C. Arango, N. Van der Wee, M.J. Kas, M. Aghajani
Published in: Neuroscience Applied, Issue 2, 2024, Page(s) 102978, ISSN 2772-4085
Publisher: Elsevier BV
DOI: 10.1016/j.nsa.2023.102978

Transdiagnostic biomarkers of allocentric spatial navigation in Alzheimer’s disease and schizophrenia: PRISM 1 study results

Author(s): S.N. Millard, A.B. Abrahams, O. Slade, A.C. Beckenstrom, B.W.J.H. Penninx, C. Arango, N. Van der Wee, A. Viera-Campos, H. Marston, M. Kas, G.R. Dawson, A. Malik
Published in: Neuroscience Applied, Issue 2, 2024, Page(s) 102679, ISSN 2772-4085
Publisher: Elsevier BV
DOI: 10.1016/j.nsa.2023.102679

Intellectual Property Rights

Other (1)

SYSTEMS AND METHODS FOR IDENTIFYING TRANSDIAGNOSTIC NEUROLOGICAL DISORDER SUBTYPES USING DNA METHYLATION MARKER ANALYSIS

Application/Publication number: 118547-5009-PR 118547-5009-PR
Date: 2023-04-26
Applicant(s): COHEN VETERANS BIOSCIENCE INC