Predicting the Impact of Monoclonal Antibodies & Vaccines on Antimicrobial Resistance

Project Information

PrIMAVeRa

Grant agreement ID: 101034420

DOI 10.3030/101034420

EC signature date 9 November 2021

Start date 1 November 2021

End date 31 October 2026

Funded under

• SOCIETAL CHALLENGES - Health, demographic change and well-being

Total cost € 9 250 000,00

EU contribution € 6 500 000,00

Coordinated by

EUROPEAN VACCINE INITIATIVE E.V
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (10)

Systematic review on economic outcomes associated with AMR
Population-based models for selected cases studies and findings on gaps in data and methods identified
Communication policy and plan for dissemination and exploitation
Registered statistical analysis plan
Systematic review and inventory of existing population-based AMR models

Systematic review and inventory of existing populationbased AMR models

Systematic review on frequency measures of burden of AMR
Systematic review on health outcomes associated with AMR
Viewpoint on conceptual and technical challenges in determining burden of AMR
Databases selected after systematic review
Kick-off meeting

Kickoff meeting

Open Research Data Pilot (1)

Updated Data repository feeding into the EPI-Net structure (https://epi-net.eu)

Updated Data repository feeding into the EPINet structure httpsepineteu

Websites, patent fillings, videos etc. (1)

Project website

Publications

Peer reviewed articles (8)

Targeted mupirocin-based decolonization for Staphylococcus aureus carriers and the subsequent risk of mupirocin resistance in haemodialysis patients – a longitudinal study over 20 years

Author(s): N. Hassoun-Kheir, N. Buetti, V. Olivier, M. Perez, J. Frossard, G. Renzi, J. Schrenzel, P. Saudan, S Harbarth
Published in: The Journal of Hospital Infection, Issue Volume 135, May 2023, 2023, Page(s) 55-58, ISSN 1532-2939
Publisher: Elsevier
DOI: 10.1016/j.jhin.2023.01.019

Using contact network dynamics to implement efficient interventions against pathogen spread in hospital settings: A modelling study

Author(s): Leclerc QJ, Duval A, Guillemot D, Opatowski L, Temime L
Published in: PLOS Medicine, Issue 21(7): e1004433, 2024, ISSN 1549-1277
Publisher: Public Library of Science
DOI: 10.1371/journal.pmed.1004433

How to: share and reuse data - challenges and solutions from PrIMAVeRa project

Author(s): Mariana Guedes, Almudena de la Serna Bazan, Elena Rubio-Martn, Lydia Barrera Pulido, Virginia Palomo, Alen Pilji, Quentin J. Leclerc, Emmanuel Aris, Venanzio Vella, Asta Dambrauskien, Julie V. Robotham, Astrid Prez, Nasreen Hassoun-Kheir, Marlieke E.A. de Kraker, Fabiana Arieti, Ruth Joanna Davis, Evelina Tacconelli, Elena Salamanca-Rivera, Jess Rodrguez-Bao
Published in: Clinical Microbiology and Infection, 2025, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2025.01.024

A systematic review on the excess health risk of antibiotic-resistant bloodstream infections for six key pathogens in Europe

Author(s): Nasreen Hassoun-Kheir, Mariana Guedes, Marie-Therese Ngo Nsoga, Lorenzo Argante, Fabiana Arieti, Beryl P. Gladstone, Rhys Kingston, Nichola R. Naylor, Maria D. Pezzani, Koen B. Pouwels, Julie V. Robotham, Jesús Rodríguez-Baño, Evelina Tacconelli, Venanzio Vella, Stephan Harbarth, Marlieke E.A. de Kraker, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Radwa A. El-Abasiri, Liliana Galia, Jer
Published in: Clinical Microbiology and Infection, Issue 30, 2024, Page(s) S14-S25, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.09.001

Excess resource use and cost of drug-resistant infections for six key pathogens in Europe: a systematic review and Bayesian meta-analysis

Author(s): Rhys Kingston, Venanzio Vella, Koen B. Pouwels, Johannes E. Schmidt, Radwa A. Abdelatif El-Abasiri, Eduardo Reyna-Villasmil, Nasreen Hassoun-Kheir, Stephan Harbarth, Jesús Rodríguez-Baño, Evelina Tacconelli, Fabiana Arieti, Beryl Primrose Gladstone, Marlieke E.A. de Kraker, Nichola R. Naylor, Julie V. Robotham, Lorenzo Argante, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Liliana Galia,
Published in: Clinical Microbiology and Infection, Issue Volume 30, Supplement 1, 2024, 2024, Page(s) S26-S36, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.12.013.

Expert consensus on antimicrobial resistance research priorities to focus development and implementation of antibacterial vaccines and monoclonal antibodies

Author(s): Nasreen Hassoun-Kheir, Mariana Guedes, Fabiana Arieti, Maria Diletta Pezzani, Beryl Primrose Gladstone, Julie V Robotham, Koen B Pouwels, Rhys Kingston, Yehuda Carmeli, Alessandro Cassini, Michele Cecchini, Francis Drobniewski, Isabel Frost, Jeroen Geurtsen, Andreas Kronenberg, Mila Nu Nu Htay, Mical Paul, Nuno Rocha-Pereira, Jesús Rodríguez-Baño, Luigia Scudeller, Andrew J Stewardson, Evelina
Published in: Eurosurveillance, Issue 29, 2024, ISSN 1560-7917
Publisher: ECDC
DOI: 10.2807/1560-7917.es.2024.29.47.2400212

Frequency of bloodstream infections caused by six key antibiotic-resistant pathogens for prioritization of research and discovery of new therapies in Europe: a systematic review

Author(s): Maria Diletta Pezzani, Fabiana Arieti, Nithya Babu Rajendran, Benedetta Barana, Eva Cappelli, Maria Elena De Rui, Liliana Galia, Nasreen Hassoun-Kheir, Lorenzo Argante, Johannes Schmidt, Jesus Rodriguez-Bano, Stephan Harbarth, Marlieke de Kraker, Beryl Primrose Gladstone, Evelina Tacconelli
Published in: Clinical Microbiology and Infection, Issue Volume 30, Supplement 1, 2024, 2024, Page(s) S4-S13, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.10.019.

Synthesizing pathogen- and infection-specific estimates of the burden of antimicrobial resistance in Europe for health-technology assessment: gaps, heterogeneity, and bias

Author(s): Julie V. Robotham, Evelina Tacconelli, Venanzio Vella, Marlieke E.A. de Kraker
Published in: Clinical Microbiology and Infection, Issue Volume 30, Supplement 1, 2024, 2024, Page(s) S1-S3, ISSN 1198-743X
Publisher: Blackwell Publishing Inc.
DOI: 10.1016/j.cmi.2023.10.004

Other (2)

Global burden of antimicrobial resistance: essential pieces of a global puzzle

Author(s): Marlieke E A de Kraker, Stephan Harbarth
Published in: The Lancet, Issue Volume 399, Issue 10344, P2347, June 25, 2022, 2022
Publisher: Elsevier
DOI: 10.1016/s0140-6736(22)00940-0

Estimating antimicrobial resistance burden in Europe—what are the next steps?

Author(s): Nasreen Hassoun-Kheir, Stephan Harbarth
Published in: The Lancet Public Health, Issue Volume 7, Issue 11, E886-E887, November 01, 2022, 2022
Publisher: Elsevier
DOI: 10.1016/s2468-2667(22)00250-x