Project description
A pump and smart patch to treat diabetes
As the prevalence of diabetes continues to increase across all ages in Europe, the life expectancy of patients suffering from Type 1 diabetes remains significantly reduced compared to healthy people. The EU-funded PRISMA project is developing an artificial pancreas as a treatment solution for patients with Type 1 diabetes. This device performs a continuous glucose measurement and pumps precise doses of insulin and other hormones needed for treatment. Specifically, a closed-loop artificial pancreas makes it possible to automatically control the blood glucose level using a mixture of multiple hormones simultaneously. The project will focus on a feasibility study to realise a small, lightweight smart patch able to deliver three hormones through silicon microneedles.
Objective
More than 30 million people are living with diabetes in the EU, with a prevalence expected to grow to over 10% of the adult population by the year 2030. Despite modern treatments, the life expectancy of patients with type 1 diabetes remains reduced as compared to healthy people due to lack of efficient therapies. An “artificial pancreas” is the ultimate solution for such therapy: a device performing a continuous glucose measurement and pumping precise doses of insulin and other hormones needed for the treatment. The closed-loop artificial pancreases promises an agile solution where the diabetes patients may effectively feel relieved from their disease as the blood glucose level is automatically controlled using a mixture of multiple hormones simultaneously. Such an innovative technology alleviates the burden of carbohydrate counting and automatically ensuring the optimal glucose level at all times. However, a small, lightweight device which is able to administrate multiple hormones is still lacking. This proposal seeks to develop a novel micro-peristaltic pump on silicon, to be integrated with a transdermal smart patch loaded with the three hormones delivered by silicon microneedles. The PRISMA innovation is possible thanks to the achievements of the FET-OPEN project “BioWings”, where the concept of thin-film micropump using actuating materials has been prototyped.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.
- medical and health sciencesclinical medicineendocrinologydiabetes
- natural sciencesbiological sciencesbiochemistrybiomoleculescarbohydrates
- medical and health sciencesmedical biotechnologytissue engineeringartificial pancreas
- natural scienceschemical sciencesinorganic chemistrymetalloids
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Keywords
Programme(s)
Call for proposal
(opens in new window) H2020-FETOPEN-2018-2020
See other projects for this callSub call
H2020-FETOPEN-2018-2019-2020-4
Funding Scheme
CSA - Coordination and support actionCoordinator
00199 Roma Rm
Italy
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.