Project description DEENESFRITPL Machine learning identifies risk factors for diabetes Diabetes affects millions of individuals worldwide, and the inability to effectively manage blood glucose levels leads to various comorbidities such as obesity and cardiovascular disease. Therefore, it is important to understand patient characteristics and develop health interventions that stimulate positive health behaviour changes. To achieve this, the EU-funded CASCARA project will employ a multi-parametric approach that includes machine learning to identify specific characteristics capable of predicting how patients respond to diabetes diagnosis. Researchers will use observational data to determine the impact of gender and socioeconomic and demographic status on the adoption of a healthy lifestyle that involves a well-balanced diet and physical activity. Show the project objective Hide the project objective Objective Diabetes causes a large and unevenly distributed health and economic burden within the population living with diabetes. Improved health behaviours have the potential to avert a large share of morbidity and mortality attributable to diabetes. However, adherence to recommended self-management remains challenging for many patients. This may (at least partly) explain the large overall disease burden in people with diabetes, as well as how that burden is distributed among patients. A better understanding of the patient and community level characteristics that affect behaviour change can inform more personalised, more effective health interventions that stimulate positive health behaviour changes, in turn reducing the overall burden associated with diabetes.CASCARA aims to provide novel and much needed evidence on characteristics predictive of (1) health behaviour change subsequent to a diabetes diagnosis and (2) of the resulting changes in diabetes complication risk factors. To achieve this, I will use causal econometric and epidemiologic methods as well as machine learning (ML) and causal mediation analysis. The commonly recommended behaviour changes I focus on comprise: improving diet, increasing physical activity, reducing smoking and alcohol consumption. In particular, CASCARA will address the following research objectives using longitudinal observational data from continental Europe, the UK and the US:1. Investigate the effect of a diabetes diagnosis on health behaviours and potential heterogeneities across gender and socioeconomic status 2. Use of ML to identify potentially unanticipated socioeconomic, demographic and clinical characteristics affecting health behaviour change, for a more detailed understanding of its potential drivers 3. Use causal mediation analysis to identify the impact of different health behaviour changes on risk factors for diabetes complications (body mass index, hypertension status and blood glucose levels) post-diabetes diagnosis. Fields of science social sciencessociologydemographymortalitymedical and health sciencesclinical medicineendocrinologydiabetesmedical and health scienceshealth sciencesnutritionnatural scienceschemical sciencesorganic chemistryalcoholsnatural sciencescomputer and information sciencesartificial intelligencemachine learning Keywords machine learning diabetes Programme(s) H2020-EU.4. - SPREADING EXCELLENCE AND WIDENING PARTICIPATION Main Programme Topic(s) WF-03-2020 - Widening Fellowships Call for proposal H2020-WF-2018-2020 See other projects for this call Sub call H2020-WF-03-2020 Funding Scheme MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF) Coordinator LISER - LUXEMBOURG INSTITUTE OF SOCIO-ECONOMIC RESEARCH Net EU contribution € 178 320,00 Address 11 PORTE DES SCIENCES CAMPUS BLEVAL 4366 Esch Sur Alzette Luxembourg See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Luxembourg Luxembourg Luxembourg Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 178 320,00
