REVERT Regeneration as a Vulnerable State for Microbe-Driven Injury and Tumorigenesis

Project Information

REVERT

Grant agreement ID: 101040453

DOI

10.3030/101040453

EC signature date 17 November 2022

Start date 1 January 2023

End date 31 January 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 426 714,00

EU contribution

€ 1 426 714,00

Coordinated by

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Scientific Reports

Author(s): Felix Bolduan; Niklas Müller-Bötticher; Olivia Debnath; Ines Eichhorn; Yvonne Giesecke; Alexandra Wetzel; Shashwat Sahay; Tomasz Zemojtel; Marten Jaeger; Ute Ungethuem; Christoph Roderburg; Catarina Alisa Kunze; Annika Lehmann; David Horst; Frank Tacke; Roland Eils; Bertram Wiedenmann; Michael Sigal; Naveed Ishaque
Published in: Scientific Reports, 2025, ISSN 2045-2322
Publisher: Springer Nature
DOI: 10.1038/S41598-025-01912-4

Elevated sortilin expression discriminates functional from non-functional neuroendocrine tumors and enables therapeutic targeting

Author(s): Felix Bolduan, Alexandra Wetzel, Yvonne Giesecke, Ines Eichhorn, Natalia Alenina, Michael Bader, Thomas E. Willnow, Bertram Wiedenmann, Michael Sigal
Published in: Frontiers in Endocrinology, Issue 15, 2024, ISSN 1664-2392
Publisher: Frontiers Media SA
DOI: 10.3389/fendo.2024.1331231

p53 terminates the regenerative fetal-like state after colitis-associated injury

Author(s): Kimberly Hartl, Şafak Bayram, Alexandra Wetzel, Christine Harnack, Manqiang Lin, Anne-Sophie Fischer, Lichao Liu, Giulia Beccaceci, Guido Mastrobuoni, Sabrina Geisberger, Martin Forbes, Benedict J. E. Monteiro, Martina Macino, Roberto E. Flores, Cornelius Engelmann, Hans-Joachim Mollenkopf, Michael Schupp, Frank Tacke, Ashley D. Sanders, Stefan Kempa, Hilmar Berger, Michael Sigal
Published in: Science Advances, Issue 10, 2024, ISSN 2375-2548
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/sciadv.adp8783

Short-term mucosal disruption enables colibactin-producing <i>E. coli</i> to cause long-term perturbation of colonic homeostasis

Author(s): Christine Harnack, Hilmar Berger, Lichao Liu, Hans-Joachim Mollenkopf, Till Strowig, Michael Sigal
Published in: Gut Microbes, Issue 15, 2024, ISSN 1949-0976
Publisher: Informa UK Limited
DOI: 10.1080/19490976.2023.2233689

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche

Author(s): Manqiang Lin, Kimberly Hartl, Julian Heuberger, Giulia Beccaceci, Hilmar Berger, Hao Li, Lichao Liu, Stefanie Müllerke, Thomas Conrad, Felix Heymann, Andrew Woehler, Frank Tacke, Nikolaus Rajewsky, Michael Sigal
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41467-023-38780-3

Human embryo models: unveiling sophisticated self-organization of stem cells during post-implantation stages

Author(s): Manqiang Lin, Michael Sigal
Published in: Signal Transduction and Targeted Therapy, Issue 8, 2023, ISSN 2059-3635
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41392-023-01677-0

Other (1)

Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration

Author(s): Julian Heuberger; Lichao Liu; Hilmar Berger; Joop van den Heuvel; Manqiang Lin; Stefanie Müllerke; Safak Bayram; Giulia Beccaceci; Hugo de Jonge; Ermanno Gherardi; Michael Sigal
Published in: Nature Communications, 2025
Publisher: Springer Nature
DOI: 10.1038/S41467-025-59474-Y