FROM SINGLE MOLECULES TO CELL REPROGRAMMING: DECIPHERING AND RECODING DISORDERED PIONEER TRANSCRIPTION FACTORS

Project Information

PIONEER

Grant agreement ID: 101040641

DOI

10.3030/101040641

EC signature date 10 October 2022

Start date 1 January 2023

End date 31 December 2027

Funded under

• European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Thesis and dissertations (1)

The Structural Dynamics of Sox2: Deciphering the Role of Intrinsically Disordered Regions in Pioneer Transcription Factors

Author(s): Sveinn Bjarnason
Published in: 2024
Publisher: University of Iceland

Peer reviewed articles (3)

DNA binding redistributes activation domain ensemble and accessibility in pioneer factor Sox2

Author(s): Sveinn Bjarnason, Jordan A. P. McIvor, Andreas Prestel, Kinga S. Demény, Jakob T. Bullerjahn, Birthe B. Kragelund, Davide Mercadante, Pétur O. Heidarsson
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41467-024-45847-2

Multifunctional Intrinsically Disordered Regions in Transcription Factors

Author(s): Matti Már, Kateryna Nitsenko, Pétur O. Heidarsson
Published in: Chemistry – A European Journal, Issue 29, 2024, ISSN 0947-6539
Publisher: Wiley
DOI: 10.1002/chem.202203369

Human Small Heat Shock Protein B8 Inhibits Protein Aggregation without Affecting the Native Folding Process

Author(s): Dhawal Choudhary, Laura Mediani, Mario J. Avellaneda, Sveinn Bjarnason, Simon Alberti, Edgar E. Boczek, Pétur O. Heidarsson, Alessandro Mossa, Serena Carra, Sander J. Tans, Ciro Cecconi
Published in: Journal of the American Chemical Society, Issue 145, 2023, ISSN 0002-7863
Publisher: American Chemical Society (ACS)
DOI: 10.1021/jacs.3c02022