Fluorescent probes and degraders of the sterol transport protein Aster-A
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Author(s):
Nianzhe He, Laura Depta, Sonja Sievers, Luca Laraia
Published in:
Bioorganic & Medicinal Chemistry, Issue 103, 2024, ISSN 0968-0896
Publisher:
Elsevier BV
DOI:
10.1016/j.bmc.2024.117673
Unifying principles for the design and evaluation of natural product-inspired compound collections
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Author(s):
Frederik Simonsen Bro; Luca Laraia
Published in:
Chemical Science, 2025, ISSN 2041-6539
Publisher:
Royal Society of Chemistry
DOI:
10.1039/D4SC08017C
Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters
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Author(s):
Laura Depta, Hogan P. Bryce-Rogers, Nienke J. Dekker, Anna Wiehl Bønke, Nicolò Camporese, Mingxing Qian, Yuanjian Xu, Douglas F. Covey, Luca Laraia
Published in:
Journal of Lipid Research, Issue 66, 2025, ISSN 0022-2275
Publisher:
Elsevier BV
DOI:
10.1016/J.JLR.2024.100738
Identification of a Privileged Scaffold for Inhibition of Sterol Transport Proteins through the Synthesis and Ring Distortion of Diverse, Pseudo-Natural Products
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Author(s):
Frederik Simonsen Bro; Laura Depta; Nienke J. Dekker; Hogan P. Bryce-Rogers; Maria Lillevang Madsen; Kaia Fiil Præstegaard; Tino Petersson; Thomas Whitmarsh-Everiss; Mariusz Kubus; Luca Laraia
Published in:
ACS Central Science, 2025, ISSN 2374-7951
Publisher:
American Chemical Society
DOI:
10.1021/ACSCENTSCI.4C01657
