Gene expression dosage as a driver of cellular and physiological traits

Project Information

DOSAGE2FUNC

Grant agreement ID: 101043238

DOI

10.3030/101043238

EC signature date 20 June 2022

Start date 1 July 2022

End date 30 June 2027

Funded under

• European Research Council (ERC)

Total cost

€ 1 993 059,00

EU contribution

€ 1 993 059,00

Coordinated by

KUNGLIGA TEKNISKA HOEGSKOLAN
Sweden

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Research Data Management

Publications

Peer reviewed articles (4)

eLife

Author(s): Júlia DomingoMariia MinaevaJohn A MorrisSam GhatanMarcello ZiosiNeville E SanjanaTuuli Lappalainen
Published in: eLife, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications Ltd.
DOI: 10.7554/ELIFE.100555.1

Genetic and molecular architecture of complex traits

Author(s): Tuuli Lappalainen, Yang I Li, Sohini Ramachandran, Alexander Gusev
Published in: Cell, 2024, ISSN 1097-4172
Publisher: Cell Press
DOI: 10.1016/j.cell.2024.01.023

Specifying cellular context of transcription factor regulons for exploring context-specific gene regulation programs

Author(s): Mariia Minaeva, Júlia Domingo, Philipp Rentzsch, Tuuli Lappalainen
Published in: NAR Genomics and Bioinformatics, Issue 7, 2025, ISSN 2631-9268
Publisher: Oxford University Press (OUP)
DOI: 10.1093/NARGAB/LQAE178

Molecular quantitative trait loci

Author(s): François Aguet; Kaur Alasoo; Yang I. Li; Alexis Battle; Hae Kyung Im; Stephen B. Montgomery; Tuuli Lappalainen
Published in: Nature Reviews Methods Primers, 2023, ISSN 2662-8449
Publisher: Springer Nature
DOI: 10.1038/S43586-022-00188-6

Other (3)

Non-linear transcriptional responses to gradual modulation of transcription factor dosage

Author(s): Júlia Domingo, Mariia Minaeva, John A Morris, Sam Ghatan, Marcello Ziosi, Neville E Sanjana, Tuuli Lappalainen
Published in: 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.03.01.582837

Recalibrating differential gene expression by genetic dosage variance prioritizes functionally relevant genes

Author(s): Philipp Rentzsch, Aaron Kollotzek, Pejman Mohammadi, Tuuli Lappalainen
Published in: 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.04.10.588830

Specifying cellular context of transcription factor regulons for exploring context-specific gene regulation programs

Author(s): Mariia Minaeva, Júlia Domingo, Philipp Rentzsch, Tuuli Lappalainen
Published in: 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.12.31.573765