Metastable Epiallele: Role of Epigenetic Variability for the Development of Metabolic and Endocrine Diseases

Project Information

E-VarEndo

Grant agreement ID: 101043991

DOI

10.3030/101043991

EC signature date 25 October 2022

Start date 1 February 2023

End date 31 January 2028

Funded under

• European Research Council (ERC)

Total cost

€ 1 997 969,00

EU contribution

€ 1 997 969,00

Coordinated by

CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Relevance and consequence of chronic inflammation for obesity development

Author(s): Lisa Ruck; Susanna Wiegand; Peter Kühnen
Published in: Molecular and Cellular Pediatrics, 2023, ISSN 2194-7791
Publisher: Heidelberg: Springer
DOI: 10.1186/S40348-023-00170-6

Hypothalamic obesity: from basic mechanisms to clinical perspectives

Author(s): Jesús Argente, I Sadaf Farooqi, Julie A Chowen, Peter Kühnen, Miguel López, Eugenia Morselli, Hoong-Wei Gan, Helen A Spoudeas, Martin Wabitsch, Manuel Tena-Sempere
Published in: The Lancet Diabetes & Endocrinology, Issue 13, 2025, ISSN 2213-8587
Publisher: Elsevier BV
DOI: 10.1016/S2213-8587(24)00283-3

Stem Cell Research

Author(s): Katarzyna A. Ludwik; Robert Opitz; Sabine Jyrch; Matthias Megges; Peter Kühnen; Harald Stachelscheid
Published in: Stem Cell Research, 2025, ISSN 1873-5061
Publisher: Elsevier
DOI: 10.1016/J.SCR.2025.103698

Scientific Reports

Author(s): Adina Sophie Graffunder; Audrey Amber Julie Bresser; Valeria Fernandez Vallone; Matthias Megges; Harald Stachelscheid; Peter Kühnen; Robert Opitz
Published in: Scientific Reports, 2023, ISSN 2045-2322
Publisher: Nature Portfolio
DOI: 10.1038/S41598-024-59533-2

Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment

Author(s): Lara Lechner, Robert Opitz, Matt J. Silver, Philipp M. Krabusch, Andrew M. Prentice, Martha S. Field, Harald Stachelscheid, Elsa Leitão, Christopher Schröder, Valeria Fernandez Vallone, Bernhard Horsthemke, Karl-Heinz Jöckel, Börge Schmidt, Markus M. Nöthen, Per Hoffmann, Stefan Herms, Patrick W. Kleyn, Matthias Megges, Ulrike Blume-Peytavi, Katja Weiss, Knut Mai, Oliver Blankenstein, Benedikt Obermayer, Susanna Wiegand, Peter Kühnen
Published in: Science Translational Medicine, Issue 15, 2024, ISSN 1946-6234
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCITRANSLMED.ADG1659