Scalable systems modelling to simulate body-level interplays among non-communicable diseases

Project Information

O-Health

Grant agreement ID: 101044828

DOI 10.3030/101044828

EC signature date 27 October 2022

Start date 1 November 2022

End date 31 October 2027

Funded under

• European Research Council (ERC)

Total cost € 1 998 865,00

EU contribution € 1 998 865,00

Coordinated by

UNIVERSIDAD POMPEU FABRA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan

Publications

Peer reviewed articles (10)

Nucleus pulposus cell network modelling in the intervertebral disc

Author(s): Sofia Tseranidou, Maria Segarra-Queralt, Francis Kiptengwer Chemorion, Christine Lyn Le Maitre, Janet Piñero, Jérôme Noailly
Published in: npj Systems Biology and Applications, Issue 11, 2025, ISSN 2056-7189
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41540-024-00479-6

Physics of Life Reviews

Author(s): Maria Segarra-Queralt; Katherine Crump; Andreu Pascuet-Fontanet; Benjamin Gantenbein; Jérôme Noailly
Published in: Physics of Life Reviews, 2024, ISSN 1571-0645
Publisher: Elsevier
DOI: 10.48350/193145

Characterization of clinical data for patient stratification in moderate osteoarthritis with support vector machines, regulatory network models, and verification against osteoarthritis Initiative data

Author(s): Maria Segarra-Queralt, Mar Galofré, Laura Tio, Jordi Monfort, Joan Carlos Monllau, Gemma Piella, Jérôme Noailly
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41598-024-62212-x

Parallel Networks to simulate complex multicellular dynamics - A proof of concept with intervertebral disc cell systems

Author(s): Laura Baumgartner, Miguel Angel Gonzalez Ballester, Jerome Noailly
Published in: 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.08.08.503195

Parallel Networks to Predict <scp>TIMP</scp> and Protease Cell Activity of Nucleus Pulposus Cells Exposed and Not Exposed to Pro‐Inflammatory Cytokines

Author(s): L. Baumgartner, S. Witta, J. Noailly
Published in: JOR SPINE, Issue 8, 2025, ISSN 2572-1143
Publisher: Wiley
DOI: 10.1002/jsp2.70051

Dataset of Finite Element Models of Normal and Deformed Thoracolumbar Spine

Author(s): Morteza Rasouligandomani, Alejandro del Arco, Francis Kiptengwer Chemorion, Marc-Antonio Bisotti, Fabio Galbusera, Jérôme Noailly, Miguel A. González Ballester
Published in: Scientific Data, Issue 11, 2024, ISSN 2052-4463
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s41597-024-03351-8

Hardware Density Reduction To Avoid Proximal Junction Failure In Adult Spine Surgery: In Silico Case Studies and Virtual Cohort

Author(s): Morteza Rasouligandomani, Alex del Arco, Tomaso Villa, Luigi La Barbera, Ferran Pellise, Miguel Angel Gonzalez Ballester, Fabio Galbusera, Jerome Noailly
Published in: arXiv, 2024
Publisher: Cornell University
DOI: 10.48550/arXiv.2402.13060

Proximal Junction Failure in Spine Surgery: Integrating Geometrical and Biomechanical Global Descriptors Improves GAP Score-Based Assessment

Author(s): Morteza Rasouligandomani, Alex del Arco, Ferran Pellisé, Miguel A. González Ballester, Fabio Galbusera, Jérôme Noailly
Published in: Spine, Issue 48, 2024, ISSN 0362-2436
Publisher: Ovid Technologies (Wolters Kluwer Health)
DOI: 10.1097/BRS.0000000000004630

Network-based modelling of mechano-inflammatory chondrocyte regulation in early osteoarthritis

Author(s): Segarra-Queralt, Maria; Piella Fenoy, Gemma; Noailly, Jérôme
Published in: Frontiers in Bioengineering and Biotechnology, 2023, ISSN 2296-4185
Publisher: Frontiers Media
DOI: 10.3389/fbioe.2023.1006066

Unveiling interactions between intervertebral disc morphologies and mechanical behavior through personalized finite element modeling

Author(s): Estefano Muñoz-Moya; Morteza Rasouligandomani; Carlos Ruiz Wills; Francis Kiptengwer Chemorion; Francis Kiptengwer Chemorion; Gemma Piella; Jérôme Noailly
Published in: Frontiers in Bioengineering and Biotechnology, 2024, ISSN 2296-4185
Publisher: Frontiers Media
DOI: 10.3389/fbioe.2024.1384599

Book chapters (1)

Pixel2Mechanics: Automated Biomechanical Simulations of High-Resolution Intervertebral Discs from Anisotropic MRIs

Author(s): Sai Natarajan, Estefano Muñoz-Moya, Carlos Ruiz Wills, Gemma Piella, Jérôme Noailly, Ludovic Humbert, Miguel A. González Ballester
Published in: Lecture Notes in Computer Science, Medical Image Computing and Computer Assisted Intervention – MICCAI 2024, 2024
Publisher: Springer Nature Switzerland
DOI: 10.1007/978-3-031-72104-5_55