Tryptophan depletion sensitizes the AHR pathway by increasing AHR expression and GCN2/LAT1-mediated kynurenine uptake, and potentiates induction of regulatory T lymphocytes
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Author(s):
Solvay, M; Holfelder, P; Klaessens, S; Pilotte, L; Stroobant, V; Lamy, J; Naulaerts, S; Spillier, Q; Frédérick, R; De Plaen, E; Sers, C; Opitz, CA; Van den Eynde, BJ; Zhu, J
Published in:
Journal for ImmunoTherapy of Cancer, 2023, ISSN 2051-1426
Publisher:
BMJ Publishing Group
DOI:
10.1101/2023.01.16.524177
Biochemical Pharmacology
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Author(s):
Opitz, Christiane A.; Holfelder, Pauline; Prentzell, Mirja Tamara; Trump, Saskia
Published in:
Biochemical Pharmacology, 2023, ISSN 0006-2952
Publisher:
Elsevier BV
DOI:
10.1016/j.bcp.2023.115798