Vortex enhanced liquid chromatography for HbA1c monitoring based diabetes management in a globalized setting

Informations projet

VortexLC

N° de convention de subvention: 101047029

DOI

10.3030/101047029

Projet clôturé

Date de signature de la CE 7 Mars 2022

Date de début 1 Mars 2022

Date de fin 28 Février 2026

Financé au titre de

• The European Innovation Council (EIC)

Coût total

€ 3 014 375,75

Contribution de l’UE

€ 3 014 375,50

Coordonné par

VRIJE UNIVERSITEIT BRUSSEL
Belgium

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (9)

Technological windows for individual building blocks

Report listing and describing the relevant technical characteristics and limitations for each building block

Comparison of VortexLC prototype with commercial POC instruments

Report on cmparison of VortexLC prototype with commercial POC instruments.

Protocols for testing of demonstrator

Report describing the protocols that will be used for testing and validation of the demonstrator as a whole

Report validated specifications demonstrator

Report with validated specifications of demonstrator.

Protocols for testing of building blocks

Report describing the protocols that will be used for intermediate testing of the individual building blocks during the research and development phase of the project

Evaluation of the VortexLC prototype for the detection and identification of hemoglobin variants

Report on evaluation of the VortexLC prototype for the detection and identification of hemoglobin variants.

Method validation of the VortexLC prototype for HbA2, HbF and HbS according to CLSI guidelines

Report on method validation of the VortexLC prototype for HbA2, HbF and HbS according to CLSI guidelines.

Comparison of the Vortex LC prototype with a commercial HLPC system (Bio-Rad D100)

Report on comparison of the Vortex LC prototype with a commercial HLPC system (Bio-Rad D100).

Method validation of the VortexLC prototype for HbA1c according to the CLSI guidelines

Report on method validation of the VortexLC prototype for HbA1c according to the CLSI guidelines.

Other (1)

Approval from the Committee for Medical Ethics of UZB

Project team receives approval from the Committee for Medical Ethics of UZB for testing with human blood samples.

Websites, patent fillings, videos etc. (1)

Website

The project website is launched and first content is uploaded

Publications

Peer reviewed articles (10)

Approaches to enable vortex chromatography in silicon devices

Auteurs: Gusta Irem Sakiz, Wim De Malsche
Publié dans: Frontiers in Lab on a Chip Technologies, Numéro 5, 2026, ISSN 2813-3862
Éditeur: Frontiers Media SA
DOI: 10.3389/FRLCT.2026.1768163

Atmospheric Pressure Plasma Functionalization of Sealed PDMS Microfluidics: Application to Capillary Pumping and Enhanced Cell Growth

Auteurs: A. Zeniou, D. Kefallinou, P. Dimitrakellis, E. Xenogiannopoulou, M. Grigoriou, A. Dimoulas, D. T. Boumpas, A. Tserepi, E. Gogolides
Publié dans: ChemPlusChem, Numéro 89, 2025, ISSN 2192-6506
Éditeur: Wiley
DOI: 10.1002/CPLU.202400290

Enabling rapid parallel SERS detection with integrated microlens array

Auteurs: Sara Abbasi, Qing Liu, Dries Rosseel, Hugo Thienpont, Heidi Ottevaere
Publié dans: Sensing and Bio-Sensing Research, Numéro 48, 2025, ISSN 2214-1804
Éditeur: Elsevier BV
DOI: 10.1016/J.SBSR.2025.100808

Numerical investigation of axial dispersion reduction in chromatography using AC-electroosmotic flow in tapered geometries: Concept and numerical investigation

Auteurs: Ilyesse Bihi, Dariush Bahrami Eisaabadi, Wim De Malsche
Publié dans: Journal of Chromatography A, Numéro 1767, 2026, ISSN 0021-9673
Éditeur: Elsevier BV
DOI: 10.1016/J.CHROMA.2025.466627

A numerical study of the effects of lateral flow and retention in open tubular vortex chromatography

Auteurs: Ilyesse Bihi, Pierre Gelin, Itzchak Frankel, Wim De Malsche
Publié dans: Journal of Chromatography A, Numéro 1736, 2024, ISSN 0021-9673
Éditeur: Elsevier BV
DOI: 10.1016/j.chroma.2024.465370

Data-driven investigation of thickness variations in multilayer thin film coatings

Auteurs: Qing Liu, Tigran Baghdasaryan, Heidi Ottevaere
Publié dans: Journal of Physics: Photonics, Numéro 6, 2024, ISSN 2515-7647
Éditeur: IOP Publishing
DOI: 10.1088/2515-7647/AD8614

Plasma‐Induced Maskless Formation of Quasi‐Periodic Nanoripples on Polymeric Substrates

Auteurs: Athina S. Kastania, Sotiris Mouchtouris, Eleni Stai, Angelos Zeniou, George Kokkoris, Vassilios Constantoudis, Pavlos Tsavalas, Konstantina Mergia, Evangelos Gogolides, Angeliki Tserepi
Publié dans: Advanced Engineering Materials, Numéro 27, 2025, ISSN 1438-1656
Éditeur: Wiley
DOI: 10.1002/ADEM.202402729

Characterizing planar SERS substrates: unraveling the link between physical characteristics and performance metrics

Auteurs: Mehdi Feizpour, Qing Liu, Tom Van der Donck, Hugo Thienpont, Wendy Meulebroeck, Heidi Ottevaere
Publié dans: Journal of Physics: Photonics, Numéro 6, 2024, ISSN 2515-7647
Éditeur: IOP Publishing
DOI: 10.1088/2515-7647/ad2528

Direct laser writing of curved SERS for light-guided enhancement

Auteurs: Mehdi Feizpour, Sara Abbasi, Hugo Thienpont, Heidi Ottevaere
Publié dans: Talanta, Numéro 283, 2024, ISSN 0039-9140
Éditeur: Elsevier BV
DOI: 10.1016/J.TALANTA.2024.127130

Classification of hemoglobin fractions in the liquid state using Raman spectroscopy combined with machine learning

Auteurs: Sara Abbasi, Mehdi Feizpour, Ilse Weets, Qing Liu, Hugo Thienpont, Francesco Ferranti, Heidi Ottevaere
Publié dans: Microchemical Journal, Numéro 194, 2024, ISSN 0026-265X
Éditeur: Elsevier BV
DOI: 10.1016/j.microc.2023.109305

Conference proceedings (1)

Automatic optimization of spectral classifiers’ hyperparameters for pathogen identification through evolutionary techniques

Auteurs: Mehdi Feizpour, Sara Abbasi, Thomas Demuyser, Qing Liu, Hugo Thienpont, Wendy Meulebroeck, Heidi Ottevaere
Publié dans: Data Science for Photonics and Biophotonics, 2024
Éditeur: SPIE
DOI: 10.1117/12.3016250