Revealing the Landscape of Synaptic Diversity by Cell type- and Synapse-specific Proteomics and Transcriptomics

Project Information

DiverseSynapse

Grant agreement ID: 101054512

DOI

10.3030/101054512

Project terminated on 31 July 2026

EC signature date 4 May 2022

Start date 1 August 2022

End date 31 July 2027

Funded under

• European Research Council (ERC)

Total cost

€ 2 498 575,00

EU contribution

€ 2 498 575,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

A multi-omics view of neuronal subcellular protein synthesis

Author(s): Chao Sun, Erin Schuman
Published in: Current Opinion in Neurobiology, Issue 80, 2023, ISSN 0959-4388
Publisher: Elsevier BV
DOI: 10.1016/j.conb.2023.102705

An integrated transcriptomic and proteomic map of the mouse hippocampus at synaptic resolution

Author(s): Eva Kaulich, Quinn Waselenchuk, Nicole Fürst, Kristina Desch, Janus Mosbacher, Elena Ciirdaeva, Marcel Juengling, Roshni Ray, Belquis Nassim-Assir, Georgi Tushev, Julian D. Langer, Erin M. Schuman
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41467-025-63119-5

Cell type-specific in vivo proteomes with a multicopy mutant methionyl tRNA synthetase mouse line

Author(s): Rodrigo Alvarez-Pardo, Susanne tom Dieck, Kristina Desch, Belquis Nassim Assir, Cristina Olmedo Salinas, Riya S. Sivakumar, Julian D. Langer, Erin M. Schuman, Beatriz Alvarez-Castelao
Published in: Lab Animal, Issue 54, 2025, ISSN 0093-7355
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41684-025-01589-2

Localized mRNAs and protein synthesis in cortical layer 1

Author(s): Teresa Spanò, Belquis Nassim-Assir, Eva Kaulich, Georgi Tushev, Nicole Fürst, Helene Will, Lucija Marić, Elena Ciirdaeva, Erin M. Schuman
Published in: Cell Reports, Issue 45, 2026, ISSN 2211-1247
Publisher: Elsevier BV
DOI: 10.1016/J.CELREP.2026.117687

Neuronal processes contain the essential components for the late steps of ribosome biogenesis

Author(s): Claudia M. Fusco, Anja Staab, Ashley M. Bourke, Georgi Tushev, Kristina Desch, Erico Moreto Lins, Elena Ciirdaeva, Susanne tom Dieck, Nina Kaltenschnee, Alexander Heckel, Julian D. Langer, Erin M. Schuman
Published in: Proceedings of the National Academy of Sciences, Issue 122, 2025, ISSN 0027-8424
Publisher: National Academy of Sciences
DOI: 10.1073/PNAS.2502424122

De-centralizing the Central Dogma: mRNA translation in space and time

Author(s): Ashley M. Bourke, Andre Schwarz, Erin M. Schuman
Published in: Molecular Cell, Issue 83, 2023, ISSN 1097-2765
Publisher: Elsevier BV
DOI: 10.1016/j.molcel.2022.12.030

The proteomic landscape of synaptic diversity across brain regions and cell types

Author(s): Marc van Oostrum; Thomas Blok; Stefano L. Giandomenico; Susanne tom Dieck; Georgi Tushev; Nicole Fürst; Julian Langer; Erin M. Schuman
Published in: Cell, 2023, ISSN 1097-4172
Publisher: Cell Press
DOI: 10.1016/j.cell.2023.09.028

Other (1)

Single-synapse transcriptomics identifies cell-type- and plasticity-dependent synaptic diversity

Author(s): 7. Perez, J., Juengling, M., Kaulich, E., Korelidou, M., tom Dieck, S., Verdaasdonk, K., Fürst, N., van Oostrum, M., Adrian, R., Tushev, G., Ciirdaeva, E. & Schuman, E. M.
Publisher: Manuscript