Structural Basis for Centromere-Mediated Control of Error-free Chromosome Segregation

Project Information

CHROMSEG

Grant agreement ID: 101054950

DOI

10.3030/101054950

EC signature date 8 December 2022

Start date 1 March 2023

End date 29 February 2028

Funded under

• European Research Council (ERC)

Total cost

€ 2 209 886,00

EU contribution

€ 2 209 886,00

Coordinated by

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Structural basis for Mis18 complex assembly and its implications for centromere maintenance

Author(s): Reshma Thamkachy; Bethan Medina-Pritchard; Sang Ho Park; Carla G Chiodi; Juan Zou; Maria de la Torre-Barranco; Kazuma Shimanaka; Maria Alba Abad; Cristina Gallego Páramo; Regina Feederle; Emilija Ruksenaite; Patrick Heun; Owen R Davies; Juri Rappsilber; Dina Schneidman-Duhovny; Uhn-Soo Cho; A Arockia Jeyaprakash
Published in: EMBO Reports, 2024, ISSN 1469-3178
Publisher: EMBO press
DOI: 10.1038/S44319-024-00183-W

Current Biology

Author(s): Nitobe London; Bethan Medina-Pritchard; Christos Spanos; Juri Rappsilber; A. Arockia Jeyaprakash; Robin C. Allshire
Published in: Current Biology, 2023, ISSN 0960-9822
Publisher: Cell Press
DOI: 10.1016/J.CUB.2023.08.063

An Oryza-specific histone H4 variant predisposes H4 lysine 5 acetylation to modulate salt stress responses

Author(s): Vivek Hari-Sundar Gandhivel, Paula Sotelo-Parrilla, Steffi Raju, Shaileshanand Jha, Anjitha Gireesh, Chitthavalli Y. Harshith, Fabian Gut, Kutti R. Vinothkumar, Frédéric Berger, A. Arockia Jeyaprakash, P. V. Shivaprasad
Published in: Nature Plants, Issue 11, 2025, ISSN 2055-0278
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/S41477-025-01974-2

Functional Plasticity in Chromosome-Microtubule Coupling on the Evolutionary Time Scale

Author(s): Sundar Ram Sankaranarayanan; Satya Dev Polisetty; Kuladeep Das; Arti Dumbrepatil; Bethan Medina-Pritchard; Martin Singleton; A Arockia Jeyaprakash; Kaustuv Sanyal
Published in: Life Science Alliance, 2022, ISSN 2575-1077
Publisher: EMBO press, Rockefeller University Press and Cold Spring Harbor Laboratory Press
DOI: 10.26508/LSA.202201720

PLoS Genetics

Author(s): Koly Aktar; Thomas Davies; Ioanna Leontiou; Ivan Clark; Christos Spanos; Edward Wallace; Laura Tuck; A. Arockia Jeyaprakash; Kevin G. Hardwick
Published in: PLOS Genetics, 2024, ISSN 1553-7390
Publisher: PLoS
DOI: 10.1371/JOURNAL.PGEN.1011302

Rules of engagement for condensins and cohesins guide mitotic chromosome formation

Author(s): Kumiko Samejima, Johan H. Gibcus, Sameer Abraham, Fernanda Cisneros-Soberanis, Itaru Samejima, Alison J. Beckett, Nina Puǎčeková, Maria Alba Abad, Christos Spanos, Bethan Medina-Pritchard, James R. Paulson, Linfeng Xie, A. Arockia Jeyaprakash, Ian A. Prior, Leonid A. Mirny, Job Dekker, Anton Goloborodko, William C. Earnshaw
Published in: Science, Issue 388, 2025, ISSN 0036-8075
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIENCE.ADQ1709

PLK1-mediated phosphorylation cascade activates Mis18 complex to ensure centromere inheritance

Author(s): Pragya Parashara, Bethan Medina-Pritchard, Maria Alba Abad, Paula Sotelo-Parrilla, Reshma Thamkachy, David Grundei, Juan Zou, Christos Spanos, Chandni Natalia Kumar, Claire Basquin, Vimal Das, Zhaoyue Yan, Asma Abdullah Al-Murtadha, David A. Kelly, Toni McHugh, Axel Imhof, Juri Rappsilber, A. Arockia Jeyaprakash
Published in: Science, Issue 385, 2024, ISSN 0036-8075
Publisher: American Association for the Advancement of Science (AAAS)
DOI: 10.1126/SCIENCE.ADO8270

Substrate recognition principles for the PP2A-B55 protein phosphatase

Author(s): Thomas Kruse; Dimitriya H. Garvanska; Julia K. Varga; William Garland; Brennan C. McEwan; Jamin B. Hein; Melanie Bianca Weisser; Iker Benavides-Puy; Camilla Bachman Chan; Paula Sotelo-Parrilla; Blanca Lopez Mendez; A. Arockia Jeyaprakash; Ora Schueler-Furman; Torben Heick Jensen; Arminja N. Kettenbach; Jakob Nilsson
Published in: Science Advances, 2024, ISSN 2375-2548
Publisher: Science Press
DOI: 10.1101/2024.02.10.579793

Nature Communications

Author(s): Avinash V. Dharmadhikari; Maria Alba Abad; Sheraz Khan; Reza Maroofian; Tristan T. Sands; Farid Ullah; Itaru Samejima; Yanwen Shen; Martin A. Wear; Kiara E. Moore; Elena Kondakova; Natalia Mitina; Theres Schaub; Grace K. Lee; Christine H. Umandap; Sara M. Berger; Alejandro D. Iglesias; Bernt Popp; Rami Abou Jamra; Heinz Gabriel; Stefan Rentas; Alyssa L. Rippert; Christopher Gray; Kosuke Izumi; Laura K. Conlin; Daniel C. Koboldt; Theresa Mihalic Mosher; Scott E. Hickey; Dara V. F. Albert; Haley Norwood; Amy Feldman Lewanda; Hongzheng Dai; Pengfei Liu; Tadahiro Mitani; Dana Marafi; Hatice Koçak Eker; Davut Pehlivan; Jennifer E. Posey; Natalie C. Lippa; Natalie Vena; Erin L. Heinzen; David B. Goldstein; Cyril Mignot; Jean-Madeleine de Sainte Agathe; Nouriya Abbas Al-Sannaa; Mina Zamani; Saeid Sadeghian; Reza Azizimalamiri; Tahere Seifia; Maha S. Zaki; Ghada M. H. Abdel-Salam; Mohamed S. Abdel-Hamid; Lama Alabdi; Fowzan Sami Alkuraya; Heba Dawoud; Aya Lofty; Peter Bauer; Giovanni Zifarelli; Erum Afzal; Faisal Zafar; Stephanie Efthymiou; Daniel Gossett; Meghan C. Towne; Raey Yeneabat; Belen Perez-Duenas; Ana Cazurro-Gutierrez; Edgard Verdura; Veronica Cantarin-Extremera; Ana do Vale Marques; Aleksandra Helwak; David Tollervey; Sandeep N. Wontakal; Vimla S. Aggarwal; Jill A. Rosenfeld; Victor Tarabykin; Shinya Ohta; James R. Lupski; Henry Houlden; William C. Earnshaw; Erica E. Davis; A. Arockia Jeyaprakash; Jun Liao
Published in: Nature Communications, 2025, ISSN 2041-1723
Publisher: Nature Press
DOI: 10.1038/S41467-025-56876-W