Contextual specification of fibroblast-driven causalities in chronic intestinal inflammation and fibrosis

Project Information

BecomingCausal

Grant agreement ID: 101055093

DOI

10.3030/101055093

EC signature date 13 May 2022

Start date 1 June 2022

End date 31 May 2027

Funded under

• European Research Council (ERC)

Total cost

€ 2 411 000,00

EU contribution

€ 2 411 000,00

Coordinated by

EREVNITIKO KENTRO VIOIATRIKON EPISTIMON ALEXANDROS FLEMINGK
Greece

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Other (1)

Cellular complexity and crosstalk in murine TNF-dependent ileitis: Different fibroblast subsets propel spatially defined ileal inflammation through TNFR1 signalling

Author(s): Iliopoulou, L., Tzaferis, C., Prados, A., Roumelioti, F., Koliaraki, V., & Kollias, G.
Published in: bioRxiv, 2023, ISSN 2692-8205
Publisher: Cold spring harbor laboratory
DOI: 10.1101/2023.09.29.560107

Peer reviewed articles (5)

Discovery of the First-in-Class Inhibitors of Hypoxia Up-Regulated Protein 1 (HYOU1) Suppressing Pathogenic Fibroblast Activation

Author(s): Papadopoulou, D., Mavrikaki, V., Charalampous, F., Tzaferis, C., Samiotaki, M., Papavasileiou, K. D., Afantitis, A., Karagianni, N., Denis, M. C., Sanchez, J., Lane, J. R., Faidon Brotzakis, Z., Skretas, G., Georgiadis, D., Matralis, A. N., & Kollias, G.
Published in: Angewandte Chemie - International Edition, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202319157

SCALA: A complete solution for multimodal analysis of single-cell Next Generation Sequencing data

Author(s): Tzaferis, C., Karatzas, E., Baltoumas, F. A., Pavlopoulos, G. A., Kollias, G., & Konstantopoulos, D.
Published in: Comput Struct Biotechnol J ., 2023, ISSN 2001-0370
Publisher: Elsevier
DOI: 10.1016/j.csbj.2023.10.032

Mir221/222 drive synovial hyperplasia and arthritis by targeting cell cycle inhibitors and chromatin remodeling components

Author(s): Roumelioti F, Tzaferis C, Konstantopoulos D, Papadopoulou D, Prados A, Sakkou M, Liakos A, Chouvardas P, Meletakos T, Pandis Y, Karagianni N, Denis MC, Fousteri M, Armaka M, Kollias G
Published in: eLife, 2024, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/eLife.84698

IL-23 Exerts Dominant Pathogenic Functions in Crohn's Disease-Ileitis.

Author(s): Iliopoulou L, Lianopoulou E, Kollias G.
Published in: Mucosal Immunology, 2024, ISSN 1933-0219
Publisher: Elsevier
DOI: 10.1016/j.mucimm.2024.05.008

Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis

Author(s): Papadopoulou, D., Roumelioti, F., Tzaferis, C., Chouvardas, P., Pedersen, A. K., Charalampous, F., Christodoulou-Vafeiadou, E., Ntari, L., Karagianni, N., Denis, M. C., Olsen, J. V., Matralis, A. N., & Kollias, G.
Published in: JCI insight, 2023, ISSN 2379-3708
Publisher: American Society for Clinical Investigation
DOI: 10.1172/jci.insight.165024