Decoding consequences of complex chromosomal aberrations by multi-modal single-cell deconstruction to overcome treatment-resistance cancer

Project Information

SHATTER-AML

Grant agreement ID: 101055270

DOI

10.3030/101055270

EC signature date 31 May 2022

Start date 1 July 2022

End date 30 June 2027

Funded under

• European Research Council (ERC)

Total cost

€ 2 499 375,00

EU contribution

€ 2 499 375,00

Coordinated by

DEUTSCHES KREBSFORSCHUNGSZENTRUM HEIDELBERG
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in <i>DNMT3A</i>mut<i>NPM1</i>mut AMLs

Author(s): Elisa Donato; Nadia Correia; Carolin Andresen; Darja Karpova; Roberto Würth; Corinna Klein; Markus Sohn; Adriana Przybylla; Petra Zeisberger; Kathrin Rothfelder; Helmut Salih; Halvard Bonig; Sebastian Stasik; Christoph Röllig; Anna Dolnik; Lars Bullinger; Frank Buchholz; Christian Thiede; Daniel Hübschmann; Andreas Trumpp
Published in: Crossref, 2023, ISSN 2473-9537
Publisher: ASH
DOI: 10.1182/bloodadvances.2022008497

Nature Genetics

Author(s): Aino-Maija Leppä; Karen Grimes; Hyobin Jeong; Frank Y. Huang; Alvaro Andrades; Alexander Waclawiczek; Tobias Boch; Anna Jauch; Simon Renders; Patrick Stelmach; Carsten Müller-Tidow; Darja Karpova; Markus Sohn; Florian Grünschläger; Patrick Hasenfeld; Eva Benito Garagorri; Vera Thiel; Anna Dolnik; Bernardo Rodriguez-Martin; Lars Bullinger; Krzysztof Mrózek; Ann-Kathrin Eisfeld; Alwin Krämer; Ashley D. Sanders; Jan O. Korbel; Andreas Trumpp
Published in: Nature Genetics, 2024, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/S41588-024-01999-X

Myc controls NK cell development, IL-15-driven expansion, and translational machinery

Author(s): Hanif J Khameneh; Nicolas Fonta; Alessandro Zenobi; Charlène Niogret; Pedro Ventura; Concetta Guerra; Ivo Kwee; Andrea Rinaldi; Matteo Pecoraro; Roger Geiger; Andrea Cavalli; Francesco Bertoni; Eric Vivier; Andreas Trumpp; Greta Guarda
Published in: ISSN: 2575-1077, 2023, ISSN 2575-1077
Publisher: Life Science Alliance
DOI: 10.26508/lsa.202302069

7-Dehydrocholesterol is an endogenous suppressor of ferroptosis

Author(s): Florencio Porto Freitas; Hamed Alborzinia; Ancély Ferreira dos Santos; Palina Nepachalovich; Lohans Pedrera; Omkar Zilka; Alex Inague; Corinna Klein; Nesrine Aroua; Kamini Kaushal; Bettina Kast; Svenja M. Lorenz; Viktoria Kunz; Helene Nehring; Thamara N. Xavier da Silva; Zhiyi Chen; Sena Atici; Sebastian G. Doll; Emily L. Schaefer; Ifedapo Ekpo; Werner Schmitz; Aline Horling; Peter Imming; Sayuri Miyamoto; Ann M. Wehman; Thiago C. Genaro-Mattos; Karoly Mirnics; Lokender Kumar; Judith Klein-Seetharaman; Svenja Meierjohann; Isabel Weigand; Matthias Kroiss; Georg W. Bornkamm; Fernando Gomes; Luis Eduardo Soares Netto; Manjima B. Sathian; David B. Konrad; Douglas F. Covey; Bernhard Michalke; Kurt Bommert; Ralf C. Bargou; Ana Garcia-Saez; Derek A. Pratt; Maria Fedorova; Andreas Trumpp; Marcus Conrad; José Pedro Friedmann Angeli
Published in: Crossref, 2024, ISSN 1476-4687
Publisher: Springer Nature
DOI: 10.1038/s41586-023-06878-9

A Dynamic rRNA Ribomethylome Drives Stemness in Acute Myeloid Leukemia

Author(s): Fengbiao Zhou; Nesrine Aroua; Yi Liu; Christian Rohde; Jingdong Cheng; Anna-Katharina Wirth; Daria Fijalkowska; Stefanie Göllner; Michelle Lotze; Haiyang Yun; Xiaobing Yu; Caroline Pabst; Tim Sauer; Thomas Oellerich; Hubert Serve; Christoph Röllig; Martin Bornhäuser; Christian Thiede; Claudia Baldus; Michaela Frye; Simon Raffel; Jeroen Krijgsveld; Irmela Jeremias; Roland Beckmann; Andreas Trumpp; Carsten Müller-Tidow
Published in: Crossref, 2022, ISSN 2159-8290
Publisher: AACR
DOI: 10.1158/2159-8290.cd-22-0210

Combinatorial BCL2 Family Expression in Acute Myeloid Leukemia Stem Cells Predicts Clinical Response to Azacitidine/Venetoclax

Author(s): Alexander Waclawiczek; Aino-Maija Leppä; Simon Renders; Karolin Stumpf; Cecilia Reyneri; Barbara Betz; Maike Janssen; Rabia Shahswar; Elisa Donato; Darja Karpova; Vera Thiel; Julia M. Unglaub; Susanna Grabowski; Stefanie Gryzik; Lisa Vierbaum; Richard F. Schlenk; Christoph Röllig; Michael Hundemer; Caroline Pabst; Michael Heuser; Simon Raffel; Carsten Müller-Tidow; Tim Sauer; Andreas Trumpp
Published in: Crossref, 2023, ISSN 2159-8290
Publisher: AACR
DOI: 10.1158/2159-8290.cd-22-0939