Multivalent Supramolecular Nanosystems as Dynamic Virus Blockers

Project Information

SupraVir

Grant agreement ID: 101055416

DOI

10.3030/101055416

EC signature date 19 May 2022

Start date 1 October 2022

End date 30 September 2027

Funded under

• European Research Council (ERC)

Total cost

€ 2 849 138,00

EU contribution

€ 2 849 138,00

Coordinated by

FREIE UNIVERSITAET BERLIN
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (12)

Heteromultivalent Nanogels as Highly Potent Inhibitors of <i>Pseudomonas Aeruginosa</i>

Author(s): Yuhang Jiang, Chuanxiong Nie, Boyu Zheng, Vinod Khatri, Denis Puccio, Yanping Long, Mathias Dimde, Rainer Haag, Sumati Bhatia
Published in: Angewandte Chemie International Edition, Issue 64, 2026, ISSN 1433-7851
Publisher: Wiley
DOI: 10.1002/ANIE.202513121

Functionalized Fullerene for Inhibition of SARS-CoV-2 Variants

Author(s): Taylor M. Page, Chuanxiong Nie, Lenard Neander, Tatyana L. Povolotsky, Anil Kumar Sahoo, Philip Nickl, Julia M. Adler, Obida Bawadkji, Jörg Radnik, Katharina Achazi, Kai Ludwig, Daniel Lauster, Roland R. Netz, Jakob Trimpert, Benedikt Kaufer, Rainer Haag,
Published in: Small, 2023, ISSN 1613-6829
Publisher: Wiley
DOI: 10.1002/smll.202206154

Supramolecules for Pathogen Inhibition: From Polymers to Self-Assembled Nanosystems

Author(s): Chuanxiong Nie, Christian Zoister, Guoxin Ma, Rainer Haag
Published in: Accounts of Materials Research, Issue 7, 2026, ISSN 2643-6728
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACCOUNTSMR.5C00285

Amplification of Asymmetry via Structural Transitions in Supramolecular Polymer–Surfactant Coassemblies

Author(s): Freek V. de Graaf, Christian Zoister, Boris Schade, Tarek Hilal, Xianwen Lou, Stefan Wijker, Sandra M. C. Schoenmakers, Ghislaine Vantomme, Rainer Haag, Abhishek K. Singh, E. W. Meijer
Published in: Journal of the American Chemical Society, Issue 147, 2025, ISSN 0002-7863
Publisher: American Chemical Society (ACS)
DOI: 10.1021/JACS.5C04047

Mucin-Inspired Polymeric Fibers for Herpes Simplex Virus Type 1 Inhibition

Author(s): Justin Arenhoevel, Ann-Cathrin Schmitt, Yannic Kerkhoff, Vahid Ahmadi, Elisa Quaas, Kai Ludwig, Katharina Achazi, Chuanxiong Nie, Raju Bej, Rainer Haag
Published in: Macrom.Biosci, 2024, ISSN 1616-5195
Publisher: Wiley
DOI: 10.1002/mabi.202400120

Oxidized cellulose nanofibril hydrogel as a 3D scaffold for breast tumor spheroid expansion and microenvironment modeling

Author(s): Boyu Zheng, Jingyi Tang, Chuanxiong Nie, Yuhang Jiang, Mathias Dimde, Wenzhong Li, Rainer Haag
Published in: International Journal of Biological Macromolecules, Issue 338, 2026, ISSN 0141-8130
Publisher: Elsevier BV
DOI: 10.1016/J.IJBIOMAC.2025.149716

Sulfated Cellulose Nanofiber Hydrogel with Mucus-Like Activities for Virus Inhibition

Author(s): Yanping Long, Mathias Dimde, Julia M. Adler, Ricardo Martin Vidal, Tatyana L. Povolotsky, Philip Nickl, Katharina Achazi, Jakob Trimpert, Benedikt B. Kaufer, Rainer Haag, and Chuanxiong Nie
Published in: ACS Applied Materials & Interfaces, 2024, ISSN 1944-8252
Publisher: American Chemical Society
DOI: 10.1021/acsami.4c17998

Supramolecular Architectures of Dendritic Polymers Provide Irreversible Inhibitor to Block Viral Infection

Author(s): Ehsan Mohammadifar, Matteo Gasbarri, Mathias Dimde, Chuanxiong Nie, Heyun Wang, Tatyana L. Povolotsky, Yannic Kerkhoff, Daniel Desmecht, Sylvain Prevost, Thomas Zemb, Kai Ludwig, Francesco Stellacci, Rainer Haag
Published in: Advanced Materials, 2024, ISSN 1521-4095
Publisher: Wiley
DOI: 10.1002/adma.202408294

Charge‐Driven Self‐Assembly of Cholesterol Surfactants into Biofunctional Nanodiscs with Antiviral Activity

Author(s): Yanping Long, Seyyed Mohammad Mousavifard, Xianfeng He, Roland R. Netz, Hesam Makki, Mathias Dimde, Chuanxiong Nie, Abhishek K. Singh, Rainer Haag
Published in: Angewandte Chemie International Edition, Issue 65, 2026, ISSN 1433-7851
Publisher: Wiley
DOI: 10.1002/ANIE.202516207

Self-assembled nanosheets of biocompatible polymers as universal cell-membrane mimic to block viral infection

Author(s): Ranen Etouki, Na Xing, Mathias Dimde, Chuanxiong Nie, Ievgen S. Donskyi, Kai Ludwig, Ehsan Mohammadifar, Rainer Haag
Published in: Bioactive Materials, Issue 52, 2025, ISSN 2452-199X
Publisher: Elsevier BV
DOI: 10.1016/J.BIOACTMAT.2025.06.035

Bioactive Polysulfate‐Based Nano‐Assemblies Against Virus Infection

Author(s): Guoxin Ma, Mathias Dimde, Kai Ludwig, Latifa Abidal, Julia M. Adler, Ricardo Martin Vidal, Benedikt B. Kaufer, Jakob Trimpert, Chuanxiong Nie, Rainer Haag
Published in: Small, Issue 21, 2026, ISSN 1613-6810
Publisher: Wiley
DOI: 10.1002/SMLL.202504384

Supramolecular Polymer‐Surfactant Co‐Assemblies for Multivalent HSV‐1 Inhibition

Author(s): Christian Zoister, Boris Schade, Paulina Sittinger, Xianwen Lou, Esmee de Korver, Freek V. de Graaf, Ranen Etouki, Chuanxiong Nie, Kai Licha, Kai Ludwig, Abhishek Kumar Singh, E. W. Meijer, Rainer Haag
Published in: Angewandte Chemie International Edition, 2026, ISSN 1433-7851
Publisher: Wiley
DOI: 10.1002/ANIE.8702628