Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease

Project Information

GENEGUT

Grant agreement ID: 101057491

DOI

10.3030/101057491

EC signature date 19 May 2022

Start date 1 October 2022

End date 30 September 2026

Funded under

• Health

Total cost

€ 4 601 216,25

EU contribution

€ 4 601 215,00

Coordinated by

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (1)

Data Management Plan (DMP)

Data Management Plan (DMP) (Task 7.4, UCC, M6, 48) In this document, the consortium will lay down its plan for research data management throughout the duration of the project and will deliver an update within each periodic report as well as a final version in M48.

Documents, reports (3)

Development of predictive in vitro methods for development of targeted DDS in CD patients

Development of predictive in vitro methods for development of targeted DDS in CD patients using simulated patient and animal intestinal fluids (Tasks 3.3, Lonza, M36).

Interim impact report II

Interim impact reports to provide an overview of the communication and dissemination activities achieved to date and assess their impact by means of Key Impact Pathways. (Task 6.1-2, accelCH, M18, 36).

Interim impact report I

Interim impact reports to provide an overview of the communication and dissemination activities achieved to date and assess their impact by means of Key Impact Pathways. (Task 6.1-2, accelCH, M18, 36).

Websites, patent fillings, videos etc. (2)

GENEGUT training materials I

GENEGUT training materials incl. specific workshops, best practices, modules (Task 6.1, EFCCA,M24,48).

GENEGUT website

GENEGUT website with dedicated areas for different stakeholder groups (Task 6.1, accelCH, M2).

Publications

Peer reviewed articles (5)

European Journal of Pharmaceutical Sciences

Author(s): Elisa Millet., Joseph P O’Shea, Brendan T Griffin, Camille Dumont, Vincent Jannin
Published in: European Journal of Pharmaceutical Sciences, 2025, ISSN 0928-0987
Publisher: Elsevier B.V.
DOI: 10.1016/J.EJPS.2025.107277

Tailoring Alkyl Side Chains of Ionizable Amino-Polyesters for Enhanced In Vivo mRNA Delivery

Author(s): Aida López Espinar, Lianne M. Mulder, Mohamed Elkhashab, Zahra Khan, Mariusz Czarnocki-Cieciura, Maria R. Aburto, Sonja Vucen, Piotr S. Kowalski
Published in: ACS Applied Bio Materials, Issue 8, 2025, ISSN 2576-6422
Publisher: American Chemical Society (ACS)
DOI: 10.1021/ACSABM.5C00116

Journal of Controlled Release

Author(s): Bárbara Ferreira, Cecília Ferreira, Cláudia Martins, Rute Nunes, José das Neves, Catarina Leite-Pereira, Bruno Sarmento
Published in: Journal of Controlled Release, 2024, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/J.JCONREL.2024.11.070

Trends in 3D models of inflammatory bowel disease

Author(s): Bárbara Ferreira, Andreia S. Barros, Catarina Leite-Pereira, Juliana Viegas, José das Neves, Rute Nunes, Bruno Sarmento
Published in: Biochimica et Biophysica Acta (BBA), Issue Volume 1870, Issue 3, 2024, ISSN 0925-4439
Publisher: Elsevier
DOI: 10.1016/J.BBADIS.2024.167042

State-of-the-Art and Future Perspectives in Ingestible Remotely Controlled Smart Capsules for Drug Delivery: A GENEGUT Review

Author(s): Sophia V. Hoffmann, Joseph P. O'Shea, Paul Galvin, Vincent Jannin, Brendan T. Griffin
Published in: European Journal of Pharmaceutical Sciences, 2024, ISSN 0928-0987
Publisher: Elsevier B.V.
DOI: 10.1016/J.EJPS.2024.106911