Oral delivery of encapsulated RNA nanotherapeutics for targeted treatment of ileal Crohn's disease

Información del proyecto

GENEGUT

Identificador del acuerdo de subvención: 101057491

DOI

10.3030/101057491

Fecha de la firma de la CE 19 Mayo 2022

Fecha de inicio 1 Octubre 2022

Fecha de finalización 30 Septiembre 2026

Financiado con arreglo a

• Health

Coste total

€ 4 601 216,25

Aportación de la UE

€ 4 601 215,00

Coordinado por

UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK
Ireland

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Data Management Plan (1)

Data Management Plan (DMP)

Data Management Plan (DMP) (Task 7.4, UCC, M6, 48) In this document, the consortium will lay down its plan for research data management throughout the duration of the project and will deliver an update within each periodic report as well as a final version in M48.

Documents, reports (3)

Development of predictive in vitro methods for development of targeted DDS in CD patients

Development of predictive in vitro methods for development of targeted DDS in CD patients using simulated patient and animal intestinal fluids (Tasks 3.3, Lonza, M36).

Interim impact report II

Interim impact reports to provide an overview of the communication and dissemination activities achieved to date and assess their impact by means of Key Impact Pathways. (Task 6.1-2, accelCH, M18, 36).

Interim impact report I

Interim impact reports to provide an overview of the communication and dissemination activities achieved to date and assess their impact by means of Key Impact Pathways. (Task 6.1-2, accelCH, M18, 36).

Websites, patent fillings, videos etc. (2)

GENEGUT training materials I

GENEGUT training materials incl. specific workshops, best practices, modules (Task 6.1, EFCCA,M24,48).

GENEGUT website

GENEGUT website with dedicated areas for different stakeholder groups (Task 6.1, accelCH, M2).

Publicaciones

Peer reviewed articles (5)

European Journal of Pharmaceutical Sciences

Autores: Elisa Millet., Joseph P O’Shea, Brendan T Griffin, Camille Dumont, Vincent Jannin
Publicado en: European Journal of Pharmaceutical Sciences, 2025, ISSN 0928-0987
Editor: Elsevier B.V.
DOI: 10.1016/J.EJPS.2025.107277

Tailoring Alkyl Side Chains of Ionizable Amino-Polyesters for Enhanced In Vivo mRNA Delivery

Autores: Aida López Espinar, Lianne M. Mulder, Mohamed Elkhashab, Zahra Khan, Mariusz Czarnocki-Cieciura, Maria R. Aburto, Sonja Vucen, Piotr S. Kowalski
Publicado en: ACS Applied Bio Materials, Edición 8, 2025, ISSN 2576-6422
Editor: American Chemical Society (ACS)
DOI: 10.1021/ACSABM.5C00116

Journal of Controlled Release

Autores: Bárbara Ferreira, Cecília Ferreira, Cláudia Martins, Rute Nunes, José das Neves, Catarina Leite-Pereira, Bruno Sarmento
Publicado en: Journal of Controlled Release, 2024, ISSN 0168-3659
Editor: Elsevier BV
DOI: 10.1016/J.JCONREL.2024.11.070

Trends in 3D models of inflammatory bowel disease

Autores: Bárbara Ferreira, Andreia S. Barros, Catarina Leite-Pereira, Juliana Viegas, José das Neves, Rute Nunes, Bruno Sarmento
Publicado en: Biochimica et Biophysica Acta (BBA), Edición Volume 1870, Edición 3, 2024, ISSN 0925-4439
Editor: Elsevier
DOI: 10.1016/J.BBADIS.2024.167042

State-of-the-Art and Future Perspectives in Ingestible Remotely Controlled Smart Capsules for Drug Delivery: A GENEGUT Review

Autores: Sophia V. Hoffmann, Joseph P. O'Shea, Paul Galvin, Vincent Jannin, Brendan T. Griffin
Publicado en: European Journal of Pharmaceutical Sciences, 2024, ISSN 0928-0987
Editor: Elsevier B.V.
DOI: 10.1016/J.EJPS.2024.106911