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Photonic chip based high-throughput, multi-modal and scalable optical nanoscopy platform

Project description

Innovative super-resolution optical microscopy platform

The broad application of super-resolution optical microscopy (nanoscopy) in science and medicine is hindered by complexity, cost, and limitations in throughput and choices of resolution and field-of-view. Currently, nanoscopes use glass slides to hold the sample in place and a bulky set-up for illumination and imaging. The EU-funded NanoVision project is developing an optical nanoscope based on an affordable, compact, multi-modal photonic-chip technology with high-throughput capability. The cost-effective photonic chip will be designed to hold and illuminate the sample for imaging by using a compact optical microscope. The technology will dramatically increase the throughput, reducing the cost and providing more flexibility in terms of resolution and field-of-view.

Objective

The invention of super-resolution optical microscopy (nanoscopy) has given us a glimpse of its impact in all fields of science and medical care. Imagine the new scientific discoveries that can be realized if every research and clinical laboratory is equipped with an optical nanoscope that can deliver super-resolution imaging enabling researchers a window to nanoscale biology. However, several pain points of the available solutions currently hinder wide scale penetration of optical nanoscopy, such as cost, complexity, small throughput and limited flexibility in terms of choice of resolution and field-of-view (FOV). NanoVision will fill this pressing gap in the market with an affordable, compact, multi-modal and high-throughput photonic-chip based optical nanoscopy. Present day nanoscope uses a simple glass slide to hold the sample and a complex and bulky microscope set-up to illuminate and image. We change the current paradigm to a mass-producible photonic-chip to hold and illuminate the sample and a simple and compact optical microscope to image it. Our radical idea is thus to take out laser light steering and delivery from the microscope and transfer it to a photonic-chip. Photonic-chip based nanoscopy improves the throughput by a factor of 100x, reduces the cost by a factor of 2x and provide flexibility in terms of resolution and FOV. These key differentiator of NanoVision will not only extend the present market of nanoscopy but could also open new market opportunities. Founded on two patent families, it has been brought up to TRL 4. A spin-off, Chip NanoImaging, CNI, has been incorporated. NanoVision will propel the technology to TRL 6 by developing a user-friendly prototype and validating its impact during year-long user tests. The business and market development activities will enable us to attract investments of Euro2M by 2024 with an estimated revenue of Euro60M by 2029.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

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Coordinator

CHIP NANOIMAGING AS
Net EU contribution
€ 1 467 075,00
Address
SYKEHUSVEGEN 23
9294 Troms
Norway

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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost
€ 1 467 075,00

Participants (3)

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