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Molecular Storage System (MoSS): Intelligent DNA Data Storage

Project description

Archiving information in DNA

Storing data in DNA is an attractive option given the stability of the molecule at room temperature compared to data centres. Importantly, DNA can archive several hundred megabytes of information in a minute space. The only pitfalls are the cost and speed of transferring data to and from DNA molecules. To resolve this issue, the MoSS project funded by the European Innovation Council proposes to develop an automated DNA storage system based on a novel enzymatic technique for the high-throughput synthesis of DNA. This method takes into account the fact that data storage in DNA does not require precise and error-free synthesis, which renders the process more affordable.

Objective

Molecular Storage System (MoSS): Intelligent DNA Data Storage
Several groups, including Helixworks, have demonstrated DNA storage systems over the last few years. The information stored has steadily increased from a few kilobytes to several hundred megabytes. However, current DNA synthesis techniques based on phosphonamidite chemistry are designed for manufacturing error-free DNA for biological applications. Today, synthetic DNA costs $0.001 per nucleotide, making DNA storage seven orders of magnitude more expensive than tape.
Based on results generated from the FET Open project ?OligoArchive? (grant agreement 863320), three of the participants (Helixworks Technologies Limited, Imperial College of Science Technology and Medicine, and EURECOM) are seeking to take the OligoArchive results further, through the development of MoSS ? a new DNA storage system based on a novel enzymatic technique for writing DNA at scale (this innovation was assessed by the JRC?s Market Creation Potential indicator framework as having a ?High? level of market creation potential).
In MoSS, we will investigate novel enzymatic synthesis techniques that can dramatically reduce cost of DNA synthesis by exploiting that using DNA as a data storage medium does not require precise, error-free synthesis. Our consortium members are at the forefront in both academic research (Imperial, Eurecom) in structural biology (especially DNA-binding proteins), synthetic biology, and automation (including cell-free protein synthesis), and industrial research (Helixworks) in pursuing novel, scalable, enzymatic synthesis techniques that can offer low-cost, high-throughput write path to DNA storage.

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Keywords

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Programme(s)

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Topic(s)

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Funding Scheme

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HORIZON-EIC - HORIZON EIC Grants

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Call for proposal

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(opens in new window) HORIZON-EIC-2021-TRANSITIONOPEN-01

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Coordinator

HELIXWORKS TECHNOLOGIES LIMITED
Net EU contribution

Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.

€ 2 270 000,00
Address
LEE ROAD
T23XE10 Cork
Ireland

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Southern South-West
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

€ 2 270 000,00

Participants (1)

Partners (1)

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