Non-ionizing Metabolic Imaging for predicting the effect of and guiding Therapeutic Interventions

Project Information

MITI

Grant agreement ID: 101058229

DOI

10.3030/101058229

Project closed

EC signature date 2 March 2022

Start date 1 April 2022

End date 30 September 2025

Funded under

• The European Innovation Council (EIC)

Total cost

€ 2 100 238,75

EU contribution

€ 2 100 238,00

Coordinated by

UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands

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Deliverables

Websites, patent fillings, videos etc. (1)

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Publications

Peer reviewed articles (12)

<scp>3D</scp> deuterium metabolic imaging (<scp>DMI</scp>) of the human liver at <scp>7 T</scp> using low‐rank and subspace model‐based reconstruction

Author(s): Kyung Min Nam, Ayhan Gursan, Nam G. Lee, Dennis W. J. Klomp, Jannie P. Wijnen, Jeanine J. Prompers, Arjan D. Hendriks, Alex A. Bhogal
Published in: Magnetic Resonance in Medicine, Issue 93, 2025, ISSN 0740-3194
Publisher: Wiley
DOI: 10.1002/MRM.30395

Regionally resolved cardiac metabolism using a dipole‐loop array coil for <scp>7 T ³¹P</scp>‐<scp>MRSI</scp>

Author(s): Karkouri, Jabrane; Watson, Will; Forner, Ria; Weir-McCall, Jonathan R; Horn, Tracy; Hill, Marion; Hoole, Stephen; Klomp, Dennis; Rodgers, Christopher T
Published in: Magnetic Resonance in Medicine, 2025, ISSN 1522-2594
Publisher: Wiley
DOI: 10.17863/CAM.116144

Tier‐based formalism for safety assessment of custom‐built radio‐frequency transmit coils

Author(s): Bart Romke Steensma, Alireza Sadeghi‐Tarakameh, Ettore Flavio Meliadò, Cornelis A. T. van den Berg, Dennis W. J. Klomp, Peter R. Luijten, Gregory J. Metzger, Yigitcan Eryaman, Alexander J. E. Raaijmakers
Published in: NMR in Biomedicine, Issue 36, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.4874

Measurement of metabolite levels and treatment‐induced changes in hepatic metastases of gastro‐esophageal cancer using 7‐T phosphorus magnetic resonance spectroscopic imaging

Author(s): Lieke van den Wildenberg, Bobby A. Runderkamp, Leonard W. F. Seelen, Hanneke W. M. van Laarhoven, Mark W. J. M. Gosselink, Wybe J. M. van der Kemp, Nadia Haj Mohammad, Dennis W. J. Klomp, Jeanine J. Prompers
Published in: NMR in Biomedicine, Issue 37, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.5155

Deuterium echo-planar spectroscopic imaging (EPSI) in the human liver in vivo at 7 T

Author(s): Kyung Min Nam, Ayhan Gursan, Alex A. Bhogal, Jannie P. Wijnen, Dennis W. J. Klomp, Jeanine J. Prompers, Arjan D. Hendriks
Published in: Magnetic resonance in medicine, 2023, ISSN 1522-2594
Publisher: Wiley
DOI: 10.1002/mrm.29696

Proton metabolic mapping of the brain at 7 T using a two-dimensional free induction decay–echo-planar spectroscopic imaging readout with lipid suppression

Author(s): Kyung Min Nam, Arjan D. Hendriks, Vincent O. Boer, Dennis W. J. Klomp, Jannie P. Wijnen, Alex A. Bhogal
Published in: NMR in Biomedicine, 2022, ISSN 1099-1492
Publisher: Wiley
DOI: 10.1002/NBM.4771

Prospective of <scp>³¹P MR</scp> Spectroscopy in Hepatopancreatobiliary Cancer: A Systematic Review of the Literature

Author(s): Leonard W. F. Seelen, Lieke van den Wildenberg, Wybe J. M. van der Kemp, Firdaus A. A. Mohamed Hoesein, Nadia Haj Mohammad, I. Quintus Molenaar, Hjalmar C. van Santvoort, Jeanine J. Prompers, Dennis W. J. Klomp
Published in: Journal of Magnetic Resonance Imaging, Issue 57, 2023, ISSN 1053-1807
Publisher: Wiley
DOI: 10.1002/JMRI.28372

In vivo phosphorus magnetic resonance spectroscopic imaging of the whole human liver at 7 T using a phosphorus whole‐body transmit coil and 16‐channel receive array: Repeatability and effects of principal component analysis‐based denoising

Author(s): Lieke van den Wildenberg, Ayhan Gursan, Leonard W. F. Seelen, Tijl A. van der Velden, Mark W. J. M. Gosselink, Martijn Froeling, Wybe J. M. van der Kemp, Dennis W. J. Klomp, Jeanine J. Prompers
Published in: NMR in Biomedicine, Issue 36, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.4877

Development of a Double Tuned ²H/³¹P Whole‐Body Birdcage Transmit Coil for ²H and ³¹P MR Applications From Head to Toe at 7 T

Author(s): Ayhan Gursan, Busra Kahraman‐Agir, Mark Gosselink, Dimitri Welting, Martijn Froeling, Hans Hoogduin, Evita C. Wiegers, Jeanine J. Prompers, Dennis W. J. Klomp
Published in: NMR in Biomedicine, Issue 38, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.5325

Deuterium body array for the simultaneous measurement of hepatic and renal glucose metabolism and gastric emptying with dynamic 3D deuterium metabolic imaging at 7 T

Author(s): Ayhan Gursan, Arjan D. Hendriks, Dimitri Welting, Pim A. de Jong, Dennis W. J. Klomp, Jeanine J. Prompers
Published in: NMR in Biomedicine, Issue 36, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.4926

<scp>³¹P MR</scp> Spectroscopy in the Pancreas: Repeatability, Comparison With Liver, and Pilot Pancreatic Cancer Data

Author(s): Leonard W.F. Seelen, Lieke van den Wildenberg, Ayhan Gursan, Martijn Froeling, Mark W.J.M. Gosselink, Wybe J.M. van der Kemp, Nadia Haj Mohammad, I. Quintus Molenaar, Hjalmar C. van Santvoort, Dennis W.J. Klomp, Jeanine J. Prompers
Published in: Journal of Magnetic Resonance Imaging, Issue 60, 2024, ISSN 1053-1807
Publisher: Wiley
DOI: 10.1002/JMRI.29326

An Integrated B₁⁺ Efficient Triple‐Tuned (²H/²³Na/³¹P) Body Coil at 7T

Author(s): Busra Kahraman‐Agir, Jiying Dai, Dimitri Welting, Martijn Lunenburg, Mark Gosselink, Dennis Klomp
Published in: NMR in Biomedicine, Issue 38, 2025, ISSN 0952-3480
Publisher: Wiley
DOI: 10.1002/NBM.70118